1A91
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![BU of 1a91 by Molmil](/molmil-images/mine/1a91) | SUBUNIT C OF THE F1FO ATP SYNTHASE OF ESCHERICHIA COLI; NMR, 10 STRUCTURES | Descriptor: | F1FO ATPASE SUBUNIT C | Authors: | Girvin, M.E, Rastogi, V.K, Abildgaard, F, Markley, J.L, Fillingame, R.H. | Deposit date: | 1998-04-15 | Release date: | 1998-07-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the transmembrane H+-transporting subunit c of the F1F0 ATP synthase. Biochemistry, 37, 1998
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200D
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![BU of 200d by Molmil](/molmil-images/mine/200d) | STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE | Descriptor: | DNA (5'-D(*TP*AP*AP*CP*CP*C)-3') | Authors: | Kang, C, Berger, I, Lockshin, C, Ratliff, R, Moyzis, R, Rich, A. | Deposit date: | 1995-02-16 | Release date: | 1995-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere. Proc.Natl.Acad.Sci.USA, 92, 1995
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1KNZ
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![BU of 1knz by Molmil](/molmil-images/mine/1knz) | Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer | Descriptor: | 5'-R(*UP*GP*AP*CP*C)-3', Nonstructural RNA-binding Protein 34 | Authors: | Deo, R.C, Groft, C.M, Rajashankar, K.R, Burley, S.K. | Deposit date: | 2001-12-19 | Release date: | 2002-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer. Cell(Cambridge,Mass.), 108, 2002
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2Q08
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![BU of 2q08 by Molmil](/molmil-images/mine/2q08) | Crystal structure of the protein BH0493 from Bacillus halodurans C-125 complexed with ZN | Descriptor: | BH0493 protein, ZINC ION | Authors: | Fedorov, A.A, Fedorov, E.V, Patskovsky, Y, Sauder, J.M, Burley, S.K, Raushel, F, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-05-21 | Release date: | 2007-06-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Glucoronate Isomerase from Bacillus halodurans. To be Published
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4CC6
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![BU of 4cc6 by Molmil](/molmil-images/mine/4cc6) | Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase | Descriptor: | 2-{[2-(1H-pyrazolo[3,4-c]pyridin-3-yl)-6-(trifluoromethyl)pyridin-4-yl]amino}ethanol, DNA LIGASE, SULFATE ION | Authors: | Howard, S, Amin, N, Benowitz, A.B, Chiarparin, E, Cui, H, Deng, X, Heightman, T.D, Holmes, D.J, Hopkins, A, Huang, J, Jin, Q, Kreatsoulas, C, Martin, A.C.L, Massey, F, McCloskey, L, Mortenson, P.N, Pathuri, P, Tisi, D, Williams, P.A. | Deposit date: | 2013-10-18 | Release date: | 2014-06-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Fragment-Based Discovery of 6-Azaindazoles as Inhibitors of Bacterial DNA Ligase. Acs Med.Chem.Lett., 4, 2013
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1Y54
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![BU of 1y54 by Molmil](/molmil-images/mine/1y54) | Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715 | Descriptor: | (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase | Authors: | Michaux, C, Charlier, P, Frere, J.-M, Wouters, J. | Deposit date: | 2004-12-02 | Release date: | 2005-03-29 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies J.Am.Chem.Soc., 127, 2005
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3GVN
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![BU of 3gvn by Molmil](/molmil-images/mine/3gvn) | The 1.2 Angstroem crystal structure of an E.coli tRNASer acceptor stem microhelix reveals two magnesium binding sites | Descriptor: | 5'-R(*CP*CP*UP*CP*AP*CP*C)-3', 5'-R(*GP*GP*UP*GP*AP*GP*G)-3', MAGNESIUM ION | Authors: | Eichert, A, Furste, J.P, Schreiber, A, Perbandt, M, Betzel, C, Erdmann, V.A, Forster, C. | Deposit date: | 2009-03-31 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The 1.2A crystal structure of an E. coli tRNASer)acceptor stem microhelix reveals two magnesium binding sites. Biochem.Biophys.Res.Commun., 386, 2009
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1OG2
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![BU of 1og2 by Molmil](/molmil-images/mine/1og2) | Structure of human cytochrome P450 CYP2C9 | Descriptor: | CYTOCHROME P450 2C9, HEME C | Authors: | Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. | Deposit date: | 2003-04-23 | Release date: | 2003-07-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
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7XQJ
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![BU of 7xqj by Molmil](/molmil-images/mine/7xqj) | Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation) | Descriptor: | Gap junction alpha-1 protein | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2022-05-07 | Release date: | 2023-01-25 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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7XQI
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![BU of 7xqi by Molmil](/molmil-images/mine/7xqi) | Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (FIN conformation) | Descriptor: | Gap junction alpha-1 protein | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | Deposit date: | 2022-05-07 | Release date: | 2023-01-25 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14, 2023
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4IHL
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![BU of 4ihl by Molmil](/molmil-images/mine/4ihl) | Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A | Descriptor: | (1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1 1-tetraoxatricyclo[6.2.1.0~1,6~]undec-4-yl}oxy)-1-(methoxymethyl)-4,9a-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8,9,9a-de cahydrodicyclopenta[a,d][8]annulene-1,5-diol, 14-3-3 protein zeta/delta, POTASSIUM ION, ... | Authors: | Molzan, M, Ottmann, C. | Deposit date: | 2012-12-19 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. Acs Chem.Biol., 8, 2013
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1JO4
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![BU of 1jo4 by Molmil](/molmil-images/mine/1jo4) | |
255D
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![BU of 255d by Molmil](/molmil-images/mine/255d) | |
2ESY
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![BU of 2esy by Molmil](/molmil-images/mine/2esy) | Structure and influence on stability and activity of the N-terminal propetide part of lung surfactant protein C | Descriptor: | lung surfactant protein C | Authors: | Li, J, Liepinsh, E, Almlen, A, Thyberg, J, Curstedt, T, Jornvall, H, Johansson, J. | Deposit date: | 2005-10-27 | Release date: | 2005-11-15 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C Febs J., 273, 2006
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1CPQ
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![BU of 1cpq by Molmil](/molmil-images/mine/1cpq) | CYTOCHROME C' FROM RHODOPSEUDOMONAS CAPSULATA | Descriptor: | CYTOCHROME C', PROTOPORPHYRIN IX CONTAINING FE | Authors: | Tahirov, T.H, Misaki, S, Meyer, T.E, Cusanovich, M.A, Higuchi, Y, Yasuoka, N. | Deposit date: | 1995-08-14 | Release date: | 1996-12-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | High-resolution crystal structures of two polymorphs of cytochrome c' from the purple phototrophic bacterium rhodobacter capsulatus. J.Mol.Biol., 259, 1996
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1UMR
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![BU of 1umr by Molmil](/molmil-images/mine/1umr) | Crystal structure of the platelet activator convulxin, a disulfide linked a4b4 cyclic tetramer from the venom of Crotalus durissus terrificus | Descriptor: | CONVULXIN ALPHA, CONVULXIN BETA | Authors: | Murakami, M.T, Zela, S.P, Gava, L.M, Michelan-Duarte, S, Cintra, A.C.O, Arni, R.K. | Deposit date: | 2003-08-28 | Release date: | 2003-11-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Platelet Activator Convulxin, a Disulfide Linked A4B4 Cyclic Tetramer from the Venom of Crotalus Durissus Terrificus Biochem.Biophys.Res.Commun., 310, 2003
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3PME
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![BU of 3pme by Molmil](/molmil-images/mine/3pme) | Crystal structure of the receptor binding domain of botulinum neurotoxin C/D mosaic serotype | Descriptor: | GLYCEROL, SULFATE ION, Type C neurotoxin | Authors: | Zhang, Y, Buchko, G.W, Qin, L, Robinson, H, Varnum, S.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2010-11-16 | Release date: | 2010-12-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions. Biochem.Biophys.Res.Commun., 404, 2011
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3PTY
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![BU of 3pty by Molmil](/molmil-images/mine/3pty) | Crystal structure of the C-terminal extracellular domain of Mycobacterium tuberculosis EmbC | Descriptor: | Arabinosyltransferase C, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Alderwick, L.J, Besra, G.S, Futterer, K. | Deposit date: | 2010-12-03 | Release date: | 2010-12-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module. Plos Pathog., 7, 2011
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2C9W
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![BU of 2c9w by Molmil](/molmil-images/mine/2c9w) | CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION | Descriptor: | NICKEL (II) ION, SULFATE ION, SUPPRESSOR OF CYTOKINE SIGNALING 2, ... | Authors: | Debreczeni, J.E, Bullock, A, Amos, A, Savitsky, P, Barr, A, Burgess, N, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | Deposit date: | 2005-12-14 | Release date: | 2006-02-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 103, 2006
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5XGN
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![BU of 5xgn by Molmil](/molmil-images/mine/5xgn) | Crystal structure of EGFR 696-1022 T790M/C797S in complex with Go6976 | Descriptor: | 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole, CHLORIDE ION, Epidermal growth factor receptor | Authors: | Kong, L.L, Yun, C.H. | Deposit date: | 2017-04-14 | Release date: | 2017-10-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural pharmacological studies on EGFR T790M/C797S. Biochem. Biophys. Res. Commun., 488, 2017
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1SSZ
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![BU of 1ssz by Molmil](/molmil-images/mine/1ssz) | Conformational Mapping of Mini-B: An N-terminal/C-terminal Construct of Surfactant Protein B Using 13C-Enhanced Fourier Transform Infrared (FTIR) Spectroscopy | Descriptor: | Pulmonary surfactant-associated protein B | Authors: | Waring, A.J, Walther, F.J, Gordon, L.M, Hernandez-Juviel, J.M, Hong, T, Sherman, M.A, Alonso, C, Alig, T, Braun, A, Bacon, D, Zasadzinski, J.A. | Deposit date: | 2004-03-24 | Release date: | 2004-06-15 | Last modified: | 2019-04-24 | Method: | INFRARED SPECTROSCOPY | Cite: | The role of charged amphipathic helices in the structure and function of surfactant protein B. J.Pept.Res., 66, 2005
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2Q3G
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![BU of 2q3g by Molmil](/molmil-images/mine/2q3g) | Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PDZ and LIM domain protein 7 | Authors: | Gileadi, C, Papagrigoriou, E, Elkins, J, Burgess-Brown, N, Salah, E, Gileadi, O, Umeano, C, Bunkoczi, G, von Delft, F, Uppenberg, J, Pike, A.C.W, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-30 | Release date: | 2007-06-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms Protein Sci., 19, 2010
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2XWL
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![BU of 2xwl by Molmil](/molmil-images/mine/2xwl) | Crystal structure of IspD from Mycobacterium smegmatis in complex with CTP and Mg | Descriptor: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Bjorkelid, C, Bergfors, T, Unge, T, Jones, T.A. | Deposit date: | 2010-11-04 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structural and Functional Studies on Mycobacterial Ispd Enzymes Acta Crystallogr.,Sect.D, 67, 2011
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3PXW
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![BU of 3pxw by Molmil](/molmil-images/mine/3pxw) | Crystal Structure of Ferrous NO Adduct of MauG in Complex with Pre-Methylamine Dehydrogenase | Descriptor: | 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ACETATE ION, ... | Authors: | Yukl, E.T, Goblirsch, B.R, Wilmot, C.M. | Deposit date: | 2010-12-10 | Release date: | 2011-03-23 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal Structures of CO and NO Adducts of MauG in Complex with Pre-Methylamine Dehydrogenase: Implications for the Mechanism of Dioxygen Activation. Biochemistry, 50, 2011
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1ZLT
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![BU of 1zlt by Molmil](/molmil-images/mine/1zlt) | Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog | Descriptor: | (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE, SULFATE ION, Serine/threonine-protein kinase Chk1 | Authors: | Lee, C.C, Ng, K, Wan, Y, Gray, N, Spraggon, G. | Deposit date: | 2005-05-09 | Release date: | 2006-06-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog To be Published
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