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2A8C
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BU of 2a8c by Molmil
Haemophilus influenzae beta-carbonic anhydrase
Descriptor: Carbonic anhydrase 2, SULFATE ION, ZINC ION
Authors:Cronk, J.D, Rowlett, R.S, Zhang, K.Y.J, Tu, C, Endrizzi, J.A, Lee, J, Gareiss, P.C, Preiss, J.R.
Deposit date:2005-07-07
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase
Biochemistry, 45, 2006
6VY5
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BU of 6vy5 by Molmil
Crystal structure of Nipah receptor binding protein head domain in complex with human neutralizing antibody HENV-26
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Hendra receptor binding protein antibody HENV-26 Fab heavy chain, Anti-Hendra receptor binding protein antibody HENV-26 Fab light chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-02-25
Release date:2021-01-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein.
Cell, 183, 2020
1Q86
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BU of 1q86 by Molmil
Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit.
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
6VY6
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BU of 6vy6 by Molmil
Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-26
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Hendra receptor binding protein antibody HENV-26 Fab heavy chain, ...
Authors:Dong, J, Crowe, J.E.
Deposit date:2020-02-25
Release date:2021-01-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein.
Cell, 183, 2020
5XXO
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BU of 5xxo by Molmil
Crystal structure of mutant (D286N) GH3 beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorotriose
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ...
Authors:Nakajima, M, Ishiguro, R, Tanaka, N, Abe, K, Maeda, T, Miyanaga, A, Takahash, Y, Sugimoto, N, Nakai, H, Taguchi, H.
Deposit date:2017-07-04
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Function and structure relationships of a beta-1,2-glucooligosaccharide-degrading beta-glucosidase.
FEBS Lett., 591, 2017
5XXN
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BU of 5xxn by Molmil
Crystal Structure of mutant (D286N) beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorose
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ...
Authors:Nakajima, M, Ishiguro, R, Tanaka, N, Abe, K, Maeda, T, Miyanaga, A, Takahashi, Y, Sugimono, N, Nakai, H, Taguchi, H.
Deposit date:2017-07-04
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Function and structure relationships of a beta-1,2-glucooligosaccharide-degrading beta-glucosidase.
FEBS Lett., 591, 2017
7ANQ
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BU of 7anq by Molmil
Complete PCSK9 C-ter domain in complex with VHH P1.40
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Proprotein convertase subtilisin/kexin type 9, SULFATE ION, ...
Authors:Ciccone, L, Legrand, P, Stura, E.A, Dive, V, Seidahn, N.G, Fruchart Gaillard, C.
Deposit date:2020-10-12
Release date:2021-10-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels.
Mol Metab, 67, 2022
8H5T
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BU of 8h5t by Molmil
Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-015
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb-015, Spike protein S1
Authors:Yang, J, Lin, S, Lu, G.W.
Deposit date:2022-10-13
Release date:2023-10-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.
Plos Pathog., 19, 2023
6FPY
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BU of 6fpy by Molmil
Inter-alpha-inhibitor heavy chain 1, wild type
Descriptor: GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1, MAGNESIUM ION
Authors:Briggs, D.C, Day, A.J.
Deposit date:2018-02-12
Release date:2019-02-27
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (2.339 Å)
Cite:Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
J.Biol.Chem., 2020
5C0X
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BU of 5c0x by Molmil
Structure of a 12-subunit nuclear exosome complex bound to structured RNA
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Makino, D.L, Conti, E.
Deposit date:2015-06-12
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.812 Å)
Cite:RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
1GJQ
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BU of 1gjq by Molmil
Pseudomonas aeruginosa cd1 nitrite reductase reduced cyanide complex
Descriptor: CYANIDE ION, HEME C, HEME D, ...
Authors:Nurizzo, D, Brown, K, Tegoni, M, Cambillau, C.
Deposit date:2001-08-01
Release date:2002-08-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyanide Binding to Cd(1) Nitrite Reductase from Pseudomonas Aeruginosa: Role of the Active-Site His369 in Ligand Stabilization.
Biochem.Biophys.Res.Commun., 291, 2002
8H5E
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BU of 8h5e by Molmil
Crystal structure of the MgtE TM domain in complex with Ca2+ ions at 2.5 angstrom resolution
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, Magnesium transporter MgtE
Authors:Teng, X, Sheng, D, Hattori, M.
Deposit date:2022-10-13
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ion selectivity mechanism of the MgtE channel for Mg 2+ over Ca 2 .
Iscience, 25, 2022
1GN4
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BU of 1gn4 by Molmil
H145E mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
Descriptor: MANGANESE (II) ION, SUPEROXIDE DISMUTASE
Authors:Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants
Eur.J.Biochem., 251, 1998
1GN2
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BU of 1gn2 by Molmil
S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.
Descriptor: FE (III) ION, SUPEROXIDE DISMUTASE
Authors:Bunting, K.A, Cooper, J.B, Tickle, I.J, Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Engineering of an Intersubunit Disulfide Bridge in the Iron-Superoxide Dismutase of Mycobacterium Tuberculosis.
Arch.Biochem.Biophys., 397, 2002
1Q9M
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BU of 1q9m by Molmil
Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Descriptor: ROLIPRAM, ZINC ION, cAMP-specific phosphodiesterase PDE4D2
Authors:Huai, Q, Wang, H, Sun, Y, Kim, H.Y, Liu, Y, Ke, H.
Deposit date:2003-08-25
Release date:2003-09-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Structure, 11, 2003
6W0Z
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BU of 6w0z by Molmil
Structure of KHK in complex with compound 8 (2-[(1~{S},5~{R})-3-[2-[(2~{S})-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-yl]ethanoic acid)
Descriptor: 2-[(1~{S},5~{R})-3-[2-[(2~{S})-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-yl]ethanoic acid, Ketohexokinase, SULFATE ION
Authors:Jasti, J.
Deposit date:2020-03-03
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.
J.Med.Chem., 63, 2020
6P57
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BU of 6p57 by Molmil
Crystal Structure of the Beta Subunit of Luteinizing Hormone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Lutropin subunit beta, alpha-D-mannopyranose, ...
Authors:McPherson, A.
Deposit date:2019-05-29
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:The Crystal Structure of the Beta Subunit of Luteinizing Hormone and a Model for the Intact Hormone
Curr Res Struct Biol, 2019
8H1A
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BU of 8h1a by Molmil
Crystal structure of MnmM from S. aureus in apo state (1.44 A)
Descriptor: rRNA methylase YtqB
Authors:Kim, J, Cho, G, Lee, J.
Deposit date:2022-10-01
Release date:2023-01-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.
Nucleic Acids Res., 51, 2023
8H27
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BU of 8h27 by Molmil
Crystal structure of MnmM from S. aureus complexed with SAM (2.04 A)
Descriptor: 16S rRNA (Cytosine(1402)-N(4))-methyltransferase, S-ADENOSYLMETHIONINE
Authors:Kim, J, Cho, G, Lee, J.
Deposit date:2022-10-05
Release date:2023-01-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.
Nucleic Acids Res., 51, 2023
5XKD
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BU of 5xkd by Molmil
Crystal structure of dibenzothiophene sulfone monooxygenase BdsA in complex with FMN at 2.4 angstrom
Descriptor: Dibenzothiophene desulfurization enzyme A, FLAVIN MONONUCLEOTIDE
Authors:Gu, L, Su, T, Liu, S, Su, J.
Deposit date:2017-05-07
Release date:2018-05-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structural and Biochemical Characterization of BdsA fromBacillus subtilisWU-S2B, a Key Enzyme in the "4S" Desulfurization Pathway.
Front Microbiol, 9, 2018
6P2M
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BU of 6p2m by Molmil
Crystal structure of the Caldicellulosiruptor lactoaceticus GH74 (ClGH74a) enzyme in complex with LLG xyloglucan
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, GLYCEROL, ...
Authors:Stogios, P.J, Skarina, T, Arnal, G.
Deposit date:2019-05-21
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74.
J.Biol.Chem., 294, 2019
8H26
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BU of 8h26 by Molmil
Crystal structure of MnmM from S. aureus complexed with SAH (1.50 A)
Descriptor: 16S rRNA (Cytosine(1402)-N(4))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Kim, J, Cho, G, Lee, J.
Deposit date:2022-10-05
Release date:2023-01-18
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of MnmM from S. aureus complexed with SAH (1.50 A)
To Be Published
8H99
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BU of 8h99 by Molmil
Crystal structure of E. coli ThrS catalytic domain mutant
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, IMIDAZOLE, MAGNESIUM ION, ...
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
8H9C
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BU of 8h9c by Molmil
Crystal structure of chemically modified E. coli ThrS catalytic domain 4
Descriptor: N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION
Authors:Qiao, H, Xia, M, Wang, J, Fang, P.
Deposit date:2022-10-25
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
8H0T
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BU of 8h0t by Molmil
Crystal structure of MnmM from B. subtilis complexed with SAH (1.17 A)
Descriptor: Putative rRNA methylase YtqB, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Kim, J, Lee, J, Cho, G.
Deposit date:2022-09-30
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification.
Nucleic Acids Res., 51, 2023

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