2RH8
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![BU of 2rh8 by Molmil](/molmil-images/mine/2rh8) | Structure of apo anthocyanidin reductase from vitis vinifera | Descriptor: | Anthocyanidin reductase, CHLORIDE ION | Authors: | Gargouri, M, Mauge, C, Langlois D'Estaintot, B, Granier, T, Manigan, C, Gallois, B. | Deposit date: | 2007-10-08 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure and epimerase activity of anthocyanidin reductase from Vitis vinifera. Acta Crystallogr.,Sect.D, 65, 2009
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4KK3
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![BU of 4kk3 by Molmil](/molmil-images/mine/4kk3) | YwlE arginine phosphatase - wildtype | Descriptor: | Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION | Authors: | Fuhrmann, J, Clausen, T. | Deposit date: | 2013-05-05 | Release date: | 2013-07-03 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013
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4KLB
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![BU of 4klb by Molmil](/molmil-images/mine/4klb) | Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176 | Descriptor: | 2-{[(1H-1,2,4-triazol-5-ylsulfanyl)acetyl]amino}thiophene-3-carboxamide, Cruzipain | Authors: | Fernandes, W.B, Montanari, C.A, Mckerrow, J.H. | Deposit date: | 2013-05-07 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay. Plos Negl Trop Dis, 7, 2013
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4N65
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![BU of 4n65 by Molmil](/molmil-images/mine/4n65) | Crystal structure of paAzoR1 bound to anthraquinone-2-sulphonate | Descriptor: | 9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, ... | Authors: | Ryan, A, Kaplan, E, Crescente, V, Lowe, E, Preston, G.M, Sim, E. | Deposit date: | 2013-10-11 | Release date: | 2014-06-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.816 Å) | Cite: | Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes. Plos One, 9, 2014
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4N4S
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![BU of 4n4s by Molmil](/molmil-images/mine/4n4s) | A Double Mutant Rat Erk2 in Complex With a Pyrazolo[3,4-d]pyrimidine Inhibitor | Descriptor: | 3-[2-(benzyloxy)-8-methylquinolin-6-yl]-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Mitogen-activated protein kinase 1 | Authors: | Hari, S.B, Maly, D.J, Merritt, E.A. | Deposit date: | 2013-10-08 | Release date: | 2014-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases. Chem.Biol., 21, 2014
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4N9Q
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![BU of 4n9q by Molmil](/molmil-images/mine/4n9q) | Crystal structure of paAzoR1 bound to ubiquinone-1 | Descriptor: | FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, GLYCEROL, ... | Authors: | Ryan, A, Kaplan, E, Crescente, V, Lowe, E, Preston, G.M, Sim, E. | Deposit date: | 2013-10-21 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes. Plos One, 9, 2014
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4N3V
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4KE7
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![BU of 4ke7 by Molmil](/molmil-images/mine/4ke7) | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase, dodecyl hydrogen (S)-(3-azidopropyl)phosphonate | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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4Z5P
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![BU of 4z5p by Molmil](/molmil-images/mine/4z5p) | Crystal structure of the LnmA cytochrome P450 hydroxylase from the leinamycin biosynthetic pathway of Streptomyces atroolivaceus S-140 at 1.9 A resolution | Descriptor: | Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL | Authors: | Ma, M, Lohman, J, Rudolf, J, Miller, M.D, Cao, H, Osipiuk, J, Babnigg, G, Phillips Jr, G.N, Joachimiak, A, Shen, B, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-04-02 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the LnmA cytochrome P450 hydroxylase from the leinamycin biosynthetic pathway of Streptomyces atroolivaceus S-140 To be Published
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3PZD
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![BU of 3pzd by Molmil](/molmil-images/mine/3pzd) | Structure of the myosin X MyTH4-FERM/DCC complex | Descriptor: | GLYCEROL, Myosin-X, Netrin receptor DCC | Authors: | Wei, Z, Yan, J, Pan, L, Zhang, M. | Deposit date: | 2010-12-14 | Release date: | 2011-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain Proc.Natl.Acad.Sci.USA, 108, 2011
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4KKX
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![BU of 4kkx by Molmil](/molmil-images/mine/4kkx) | Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site | Descriptor: | 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. | Deposit date: | 2013-05-06 | Release date: | 2014-01-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states. Biochemistry, 52, 2013
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4Z8C
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![BU of 4z8c by Molmil](/molmil-images/mine/4z8c) | Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Roy, R.N, Lomakin, I.B, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2015-04-08 | Release date: | 2015-05-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat.Struct.Mol.Biol., 22, 2015
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4NZ2
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![BU of 4nz2 by Molmil](/molmil-images/mine/4nz2) | Crystal structure of CYP2C9 in complex with an inhibitor | Descriptor: | (2R)-N-{4-[(3-bromophenyl)sulfonyl]-2-chlorophenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide, Cytochrome P450 2C9, GLYCEROL, ... | Authors: | Branden, G, Sjogren, T, Xue, Y. | Deposit date: | 2013-12-11 | Release date: | 2014-08-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure-based ligand design to overcome CYP inhibition in drug discovery projects. Drug Discov Today, 19, 2014
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4IKL
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![BU of 4ikl by Molmil](/molmil-images/mine/4ikl) | |
4IPB
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4IN3
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4IPM
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![BU of 4ipm by Molmil](/molmil-images/mine/4ipm) | Crystal structure of a GH7 family cellobiohydrolase from Limnoria quadripunctata in complex with thiocellobiose | Descriptor: | ACETATE ION, CALCIUM ION, GH7 family protein, ... | Authors: | McGeehan, J.E, Martin, R.N.A, Streeter, S.D, Cragg, S.M, Guille, M.J, Schnorr, K.M, Kern, M, Bruce, N.C, McQueen-Mason, S.J. | Deposit date: | 2013-01-10 | Release date: | 2013-06-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance. Proc.Natl.Acad.Sci.USA, 110, 2013
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4Y4O
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![BU of 4y4o by Molmil](/molmil-images/mine/4y4o) | Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A. | Deposit date: | 2015-02-10 | Release date: | 2015-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nat.Struct.Mol.Biol., 22, 2015
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4IPZ
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![BU of 4ipz by Molmil](/molmil-images/mine/4ipz) | SmBz bound to Cyclophilin A | Descriptor: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase A, cyclosporine SmBz-CsA | Authors: | Price, A.J, Jacques, D.A, James, L.C. | Deposit date: | 2013-01-10 | Release date: | 2013-11-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | HIV-1 evades innate immune recognition through specific cofactor recruitment. Nature, 503, 2013
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4Y91
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4NFE
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![BU of 4nfe by Molmil](/molmil-images/mine/4nfe) | Human kallikrein-related peptidase 2 in complex with benzamidine | Descriptor: | BENZAMIDINE, Kallikrein-2, SULFATE ION | Authors: | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | Deposit date: | 2013-10-31 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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4NLA
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![BU of 4nla by Molmil](/molmil-images/mine/4nla) | Structure of the central NEAT domain, N2, of the listerial Hbp2 protein, apo form | Descriptor: | Iron-regulated surface determinant protein A, SULFATE ION | Authors: | Malmirchegini, G.R, Sawaya, M.R, Clubb, R.T. | Deposit date: | 2013-11-14 | Release date: | 2014-10-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Novel Mechanism of Hemin Capture by Hbp2, the Hemoglobin-binding Hemophore from Listeria monocytogenes. J.Biol.Chem., 289, 2014
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4NTL
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4NT1
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![BU of 4nt1 by Molmil](/molmil-images/mine/4nt1) | Crystal structure of apo-form of Arabidopsis ACD11 (accelerated-cell-death 11) at 1.8 Angstrom resolution | Descriptor: | SODIUM ION, accelerated-cell-death 11 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-11-29 | Release date: | 2014-02-05 | Last modified: | 2014-02-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
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4KH8
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![BU of 4kh8 by Molmil](/molmil-images/mine/4kh8) | |