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3FJ9
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BU of 3fj9 by Molmil
Crystal structure of F85W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
4L0Z
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BU of 4l0z by Molmil
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2)
Descriptor: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ...
Authors:Tahirov, T.H.
Deposit date:2013-06-01
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of Ets1 activation by Runx1.
Leukemia, 28, 2014
3FJ8
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BU of 3fj8 by Molmil
Crystal structure of C117I mutant of Human acidic fibroblast growth factor
Descriptor: Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJD
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BU of 3fjd by Molmil
Crystal structure of L44F/F132W mutant of Human acidic fibroblast growth factor
Descriptor: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M, Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3QEI
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BU of 3qei by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite Difluorotoluene Nucleoside
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Xia, S, Konigsberg, W.H, Wang, J.
Deposit date:2011-01-20
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.178 Å)
Cite:Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue.
Biochemistry, 51, 2012
4O22
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BU of 4o22 by Molmil
Binary complex of metal-free PKAc with SP20.
Descriptor: Phosphorylated peptide pSP20., cAMP-dependent protein kinase catalytic subunit alpha.
Authors:Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.S.
Deposit date:2013-12-16
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
8CYS
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BU of 8cys by Molmil
CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYY
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BU of 8cyy by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ1
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BU of 8cz1 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
5XQM
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BU of 5xqm by Molmil
NMR solution structure of SMO1, Sumo homologue in Caenorhabditis elegans
Descriptor: Small ubiquitin-related modifier
Authors:Gowda, C.M, Surana, P, Das, R.
Deposit date:2017-06-07
Release date:2017-11-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural and functional analysis of SMO-1, the SUMO homolog in Caenorhabditis elegans
PLoS ONE, 12, 2017
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
3ZG1
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BU of 3zg1 by Molmil
NI-BOUND FORM OF M123A MUTANT OF CUPRIAVIDUS METALLIDURANS CH34 CNRXS
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Girard, E, Coves, J.
Deposit date:2012-12-13
Release date:2013-10-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Metal Sensing and Signal Transduction by Cnrx from Cupriavidus Metallidurans Ch34: Role of the Only Methionine Assessed by a Functional, Spectroscopic, and Theoretical Study
Metallomics, 6, 2014
6W0L
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BU of 6w0l by Molmil
Henipavirus W protein interacts with 14-3-3 to modulate host gene expression
Descriptor: 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide
Authors:Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C.
Deposit date:2020-03-01
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression.
J.Virol., 94, 2020
4O21
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BU of 4o21 by Molmil
Product complex of metal-free PKAc, ATP-gamma-S and SP20.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha
Authors:Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.
Deposit date:2013-12-16
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
3RI4
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BU of 3ri4 by Molmil
Ets1 cooperative binding to widely separated sites on promoter DNA
Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA
Authors:Babayeva, N.D, Mino, K, Tahirov, T.H.
Deposit date:2011-04-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Plos One, 7, 2012
4LMG
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BU of 4lmg by Molmil
Crystal structure of AFT2 in complex with DNA
Descriptor: 5'-D(*AP*AP*GP*TP*GP*CP*AP*CP*CP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*GP*GP*GP*TP*GP*CP*AP*CP*T)-3', Iron-regulated transcriptional activator AFT2, ...
Authors:Poor, C.B, Sanishvili, R, Schuermann, J.P, He, C.
Deposit date:2013-07-10
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
Proc.Natl.Acad.Sci.USA, 111, 2014
6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
4MVA
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BU of 4mva by Molmil
1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate.
Descriptor: 1,2-ETHANEDIOL, ACETYLPHOSPHATE, CHLORIDE ION, ...
Authors:Minasov, G, Kuhn, M.L, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-23
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
Plos One, 9, 2014
3WU1
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BU of 3wu1 by Molmil
Crystal structure of the ETS1-RUNX1-DNA ternary complex
Descriptor: DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), Protein C-ets-1, ...
Authors:Tahirov, T.H, Ogata, K.
Deposit date:2014-04-21
Release date:2014-08-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
5FP5
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BU of 5fp5 by Molmil
Structure of cyclin-dependent kinase 2 with small-molecule ligand 4- fluorobenzoic acid (AT222) in an alternate binding site.
Descriptor: 4-fluorobenzoic acid, ACETYL GROUP, CYCLIN-DEPENDENT KINASE 2
Authors:Jhoti, H, Ludlow, R.F, O'Reilly, M, Saini, H.K, Tickle, I.J, Verdonk, M.
Deposit date:2015-11-27
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Detection of Secondary Binding Sites in Proteins Using Fragment Screening.
Proc.Natl.Acad.Sci.USA, 112, 2015
8ADW
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BU of 8adw by Molmil
Lipidic alpha-synuclein fibril - polymorph L1C
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8ADU
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BU of 8adu by Molmil
Lipidic alpha-synuclein fibril - polymorph L1A
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8AEX
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BU of 8aex by Molmil
Lipidic alpha-synuclein fibril - polymorph L3A
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-14
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8ADV
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BU of 8adv by Molmil
Lipidic alpha-synuclein fibril - polymorph L1B
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8ADS
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BU of 8ads by Molmil
Lipidic alpha-synuclein fibril - polymorph L2B
Descriptor: Alpha-synuclein
Authors:Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
Deposit date:2022-07-11
Release date:2022-10-12
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022

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