2O9V
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2O9S
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![BU of 2o9s by Molmil](/molmil-images/mine/2o9s) | The second SH3 domain from ponsin | Descriptor: | CHLORIDE ION, Ponsin, SODIUM ION, ... | Authors: | Pinotsis, N, Wilmanns, M. | Deposit date: | 2006-12-14 | Release date: | 2007-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.83 Å) | Cite: | Paxillin and ponsin interact in nascent costameres of muscle cells J.Mol.Biol., 369, 2007
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2O88
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2O2W
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2O31
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2NUZ
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![BU of 2nuz by Molmil](/molmil-images/mine/2nuz) | crystal structure of alpha spectrin SH3 domain measured at room temperature | Descriptor: | Spectrin alpha chain, brain | Authors: | Agarwal, V, Faelber, K, Hologne, M, Chevelkov, V, Oschkinat, H, Diehl, A, Reif, B. | Deposit date: | 2006-11-10 | Release date: | 2007-05-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Comparison of MAS solid-state NMR and X-ray crystallographic data in the analysis of protein dynamics in the solid state To be Published
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2JMC
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![BU of 2jmc by Molmil](/molmil-images/mine/2jmc) | Chimer between Spc-SH3 and P41 | Descriptor: | Spectrin alpha chain, brain and P41 peptide chimera | Authors: | van Nuland, N.A.J, Candel, A.M, Martinez, J.C, Conejero-Lara, F, Bruix, M. | Deposit date: | 2006-11-02 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex Febs Lett., 581, 2007
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2JM8
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![BU of 2jm8 by Molmil](/molmil-images/mine/2jm8) | R21A Spc-SH3 free | Descriptor: | Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2JMA
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![BU of 2jma by Molmil](/molmil-images/mine/2jma) | R21A Spc-SH3:P41 complex | Descriptor: | P41 peptide, Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2JM9
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![BU of 2jm9 by Molmil](/molmil-images/mine/2jm9) | R21A Spc-SH3 bound | Descriptor: | Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2IIM
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![BU of 2iim by Molmil](/molmil-images/mine/2iim) | SH3 Domain of Human Lck | Descriptor: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ... | Authors: | Romir, J, Egerer-Sieber, C, Muller, Y.A. | Deposit date: | 2006-09-28 | Release date: | 2006-11-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs. J.Mol.Biol., 365, 2007
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2DYB
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![BU of 2dyb by Molmil](/molmil-images/mine/2dyb) | The crystal structure of human p40(phox) | Descriptor: | Neutrophil cytosol factor 4 | Authors: | Honbou, K. | Deposit date: | 2006-09-08 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding. Embo J., 26, 2007
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2DX1
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![BU of 2dx1 by Molmil](/molmil-images/mine/2dx1) | Crystal structure of RhoGEF protein Asef | Descriptor: | Rho guanine nucleotide exchange factor 4 | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-22 | Release date: | 2007-01-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism J.Biol.Chem., 282, 2007
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2J06
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2J05
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2DVJ
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![BU of 2dvj by Molmil](/molmil-images/mine/2dvj) | phosphorylated Crk-II | Descriptor: | V-crk sarcoma virus CT10 oncogene homolog, isoform a | Authors: | Kobashigawa, Y, Inagaki, F. | Deposit date: | 2006-07-31 | Release date: | 2007-05-08 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007
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2HDA
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![BU of 2hda by Molmil](/molmil-images/mine/2hda) | Yes SH3 domain | Descriptor: | Proto-oncogene tyrosine-protein kinase Yes, SULFATE ION | Authors: | Camara-Artigas, A, Luque, I, Ruiz-Sanz, J, Mateo, P.L, Martin-Garcia, J.M. | Deposit date: | 2006-06-20 | Release date: | 2007-04-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: Loop flexibility and amyloid aggregation. Febs Lett., 581, 2007
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2DRK
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2DRM
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2H8H
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![BU of 2h8h by Molmil](/molmil-images/mine/2h8h) | Src kinase in complex with a quinazoline inhibitor | Descriptor: | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src | Authors: | Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J. | Deposit date: | 2006-06-07 | Release date: | 2006-11-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006
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2DNU
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![BU of 2dnu by Molmil](/molmil-images/mine/2dnu) | Solution structure of RSGI RUH-061, a SH3 domain from human | Descriptor: | SH3 multiple domains 1 | Authors: | Ohashi, W, Hirota, H, Nagashima, T, Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-26 | Release date: | 2006-10-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of RSGI RUH-061, a SH3 domain from human to be published
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2DMO
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![BU of 2dmo by Molmil](/molmil-images/mine/2dmo) | Refined solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) | Descriptor: | Neutrophil cytosol factor 2 | Authors: | Tochio, N, Chikayama, E, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-22 | Release date: | 2006-05-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 1st SH3 domain from human Neutrophil cytosol factor 2 (NCF-2) To be Published
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2GQI
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2DL8
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2DL5
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![BU of 2dl5 by Molmil](/molmil-images/mine/2dl5) | Solution structure of the first SH3 domain of human KIAA0769 protein | Descriptor: | KIAA0769 protein | Authors: | Qin, X.R, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-17 | Release date: | 2006-10-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the first SH3 domain of human KIAA0769 protein To be published
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