5XHO
| Crystal structure of Frog M-ferritin E135K mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Jagdev, M.K, Vasudevan, D. | Deposit date: | 2017-04-21 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
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5GLC
| Crystal structure of the class A beta-lactamase PenL-tTR11 containing 20 residues insertion in omega-loop | Descriptor: | Beta-lactamase | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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5MUL
| Glycoside Hydrolase BT3686 bound to Glucuronic Acid | Descriptor: | Neuraminidase, beta-D-glucopyranuronic acid | Authors: | Munoz-Munoz, J, Cartmell, A, Terrapon, N, Henrissat, B, Gilbert, H.J. | Deposit date: | 2017-01-13 | Release date: | 2017-04-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Unusual active site location and catalytic apparatus in a glycoside hydrolase family. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MVH
| Glycoside Hydrolase BACCELL_00856 | Descriptor: | BACCELL_00856 | Authors: | Munoz-Munoz, J, Cartmell, A, Terrapon, N, Henrissat, B, Gilbert, H.J. | Deposit date: | 2017-01-16 | Release date: | 2017-04-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Unusual active site location and catalytic apparatus in a glycoside hydrolase family. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5GIT
| BTB domain of KEAP1 in complex with XX3 | Descriptor: | Kelch-like ECH-associated protein 1, [(3aS,5R,5aS,6S,8S,8aS,9S,9aR)-9-acetyloxy-8-hydroxy-5,8a-dimethyl-1-methylidene-2-oxo-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,5-b]furan-6-yl] acetate | Authors: | Zhu, L.L, Li, H.L, Wu, F.S, Xiong, R. | Deposit date: | 2016-06-25 | Release date: | 2017-06-28 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway. Antioxid. Redox Signal., 27, 2017
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5GLD
| Crystal structure of the class A beta-lactamase PenL-tTR11 in complex with CBA | Descriptor: | Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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5GOT
| Crystal structure of SP-PTP, low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes | Descriptor: | CHLORIDE ION, Low molecular weight phosphotyrosine phosphatase family protein | Authors: | Ku, B, Keum, C.W, KIim, S.J. | Deposit date: | 2016-07-29 | Release date: | 2016-09-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes Biochem.Biophys.Res.Commun., 478, 2016
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5N21
| Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand | Descriptor: | 2-[(2~{S})-1-[3-cyano-7-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidin-2-yl]ethanoic acid, B-cell lymphoma 6 protein, CHLORIDE ION | Authors: | Robb, G, Ferguson, A, Hargreaves, D. | Deposit date: | 2017-02-06 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
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5N12
| Crystal structure of TCE treated rPPEP-1 | Descriptor: | 2,2,2-tris-chloroethanol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-Pro endopeptidase, ... | Authors: | Pichlo, C, Schacherl, M, Baumann, U. | Deposit date: | 2017-02-04 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5FDF
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5NGO
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5GLA
| Crystal structure of the class A beta-lactamase PenL-tTR10 containing 10 residues insertion in omega-loop | Descriptor: | Beta-lactamase | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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5NPE
| Crystal Structure of cjAgd31B (alpha-transglucosylase from Glycoside Hydrolase Family 31) in complex with beta Cyclophellitol Aziridine probe KY358 | Descriptor: | (1~{R},2~{S},3~{S},4~{R},5~{R},6~{R})-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, OXALATE ION, ... | Authors: | Wu, L, Davies, G.J. | Deposit date: | 2017-04-16 | Release date: | 2017-08-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | 1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor. ACS Cent Sci, 3, 2017
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7QTK
| SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD down - 1-P2G3 Fab (Local) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, P2G3 Light Chain, ... | Authors: | Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D. | Deposit date: | 2022-01-14 | Release date: | 2022-08-03 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys. Nat Microbiol, 7, 2022
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7QTI
| SARS-CoV-2 S Omicron Spike B.1.1.529 - 3-P2G3 and 1-P5C3 Fabs (Global) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, ... | Authors: | Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D. | Deposit date: | 2022-01-14 | Release date: | 2022-08-03 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys. Nat Microbiol, 7, 2022
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4OVL
| Interrogating HIV integrase for compounds that bind- a SAMPL challenge | Descriptor: | 1,2-ETHANEDIOL, 3-[(E)-(2-oxidanylidene-1H-indol-3-ylidene)methyl]benzoic acid, ACETIC ACID, ... | Authors: | Peat, T.S. | Deposit date: | 2013-11-21 | Release date: | 2014-03-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Interrogating HIV integrase for compounds that bind--a SAMPL challenge. J. Comput. Aided Mol. Des., 28, 2014
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5N1X
| Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand | Descriptor: | B-cell lymphoma 6 protein, ~{N}-ethyl-5-pyridin-3-yl-pyrazolo[1,5-a]pyrimidin-7-amine | Authors: | Robb, G, Ferguson, A, Hargreaves, D. | Deposit date: | 2017-02-06 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
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7QTJ
| SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD up - 1-P2G3 and 1-P5C3 Fabs (Local) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2G3 Heavy Chain, P2G3 Light Chain, ... | Authors: | Ni, D, Lau, K, Turelli, P, Fenwick, C, Perez, L, Pojer, F, Stahlberg, H, Pantaleo, G, Trono, D. | Deposit date: | 2022-01-14 | Release date: | 2022-08-03 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys. Nat Microbiol, 7, 2022
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5N1Z
| Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine macrocyclic ligand | Descriptor: | B-cell lymphoma 6 protein, CHLORIDE ION, pyrazolo-pyrimidine macrocycle | Authors: | Robb, G, Ferguson, A, Hargreaves, D. | Deposit date: | 2017-02-06 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
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5GL9
| Crystal structure of the class A beta-lactamase PenL | Descriptor: | Beta-lactamase, GLYCEROL | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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5NA1
| NADH:quinone oxidoreductase (NDH-II) from Staphylococcus aureus - holoprotein structure - 2.32 A resolution | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, NADH dehydrogenase-like protein SAOUHSC_00878, ... | Authors: | Brito, J.A, Athayde, D, Sousa, F.M, Sena, F.V, Pereira, M.M, Archer, M. | Deposit date: | 2017-02-27 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus. Biochim. Biophys. Acta, 1858, 2017
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6V1V
| VIP3B (VIP3B_2160) adapted for crystallization | Descriptor: | Vegetative insecticidal protein | Authors: | Evdokimov, A.G, Zheng, M, Moshiri, F, Haas, J, Lowder, C. | Deposit date: | 2019-11-21 | Release date: | 2019-12-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.189 Å) | Cite: | Crystal structure of a Vip3B family insecticidal protein reveals a new fold and a unique tetrameric assembly. Protein Sci., 29, 2020
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4RCH
| Discovery of 2-Pyridyl Ureas as Glucokinase Activators | Descriptor: | 1-{3-[(2-ethylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}-3-methylurea, Glucokinase, alpha-D-glucopyranose | Authors: | Voegtli, W, Vigers, G.P.A. | Deposit date: | 2014-09-16 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of 2-pyridylureas as glucokinase activators. J.Med.Chem., 57, 2014
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5NGL
| The endo-beta1,6-glucanase BT3312 | Descriptor: | 1-DEOXYNOJIRIMYCIN, Glucosylceramidase, SODIUM ION, ... | Authors: | Basle, A, Temple, M, Cuskin, F, Lowe, E, Gilbert, H. | Deposit date: | 2017-03-17 | Release date: | 2017-05-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Bacteroidetes locus dedicated to fungal 1,6-beta-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-beta-glucanase. J. Biol. Chem., 292, 2017
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5NRK
| Crystal structure of the sixth cohesin from Acetivibrio cellulolyticus' scaffoldin B in complex with Cel5 dockerin S15I, I16N mutant | Descriptor: | CALCIUM ION, DocCel5: Type I dockerin repeat domain from A. cellulolyticus family 5 endoglucanase WP_010249057 S15I, I16N mutant, ... | Authors: | Bule, P, Najmudin, S, Fontes, C.M.G.A, Alves, V.D. | Deposit date: | 2017-04-24 | Release date: | 2018-01-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure-function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes. J. Biol. Chem., 293, 2018
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