PDB: 511 件ウェブページステータス検索Chemie searchBIRD

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1H1C	Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima 分子名称: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Vega, M.C, Fernandez, F.J, Wilmanns, M. 登録日 2002-07-08 公開日 2004-03-19 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
4EMY	Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. 分子名称: Aminotransferase class I and II, PYRIDOXAL-5'-PHOSPHATE 著者 Chang, C, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-04-12 公開日 2012-05-09 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. TO BE PUBLISHED
4EFF	Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei 分子名称: Aromatic-amino-acid aminotransferase, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-29 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei To be Published
4EU1	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-25 公開日 2012-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
1IAY	CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH COFACTOR PLP AND INHIBITOR AVG 分子名称: 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, 2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE 著者 Huai, Q, Xia, Y, Chen, Y, Callahan, B, Li, N, Ke, H. 登録日 2001-03-24 公開日 2001-04-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms J.Biol.Chem., 276, 2001
4F5J	Rational Design and Directed Evolution for Conversion of Substrate Specificity from E.coli Aspartate Aminotransferase to Tyrosine Aminotransferase: Mutant P5. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5F	Structure of Aspartate Aminotransferase Conversion to Tyrosine Aminotransferase: Chimera P1. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5M	Wild-Type E. coli Aspartate Aminotransferase: A Template For The Interconversion of Substrate Specificity and Activity To Tyrosine Aminotransferase By The JANUS Algorithm. 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5I	Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5H	Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
1IAX	CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH PLP 分子名称: 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Huai, Q, Xia, Y, Chen, Y, Callahan, B, Li, N, Ke, H. 登録日 2001-03-24 公開日 2001-04-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms J.Biol.Chem., 276, 2001
4F5L	A Theoretical Optimized Mutant for the Conversion of Substrate Specificity and Activity of Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P7. 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-05-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Janus: an algorithm for ranking functional importance of residues from protein sequence alignments. To be Published
4F4E	Crystal structure of Aromatic-amino-acid aminotransferase from Burkholderia pseudomallei covalently bound to pyridoxal phosphate 分子名称: 1,2-ETHANEDIOL, Aromatic-amino-acid aminotransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-05-10 公開日 2012-05-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Aromatic-amino-acid aminotransferase from Burkholderia pseudomallei covalently bound to pyridoxal phosphate To be Published
4F5K	Substrate Specificity Conversion of Aspartate Aminotransferase to Tyrosine Aminotransferase By The JANUS Algorithm: Chimera P6. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5G	Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2. 分子名称: Aspartate aminotransferase 著者 Addington, T.A, Fisher, A.J, Toney, M.D. 登録日 2012-05-13 公開日 2013-02-13 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
1J32	Aspartate Aminotransferase from Phormidium lapideum 分子名称: PYRIDOXAL-5'-PHOSPHATE, aspartate aminotransferase 著者 Kim, H, Sawa, Y, Hamada, K. 登録日 2003-01-17 公開日 2003-02-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies of aspartate aminotransferase from Phormidium lapideum To be Published
1IX6	Aspartate Aminotransferase Active Site Mutant V39F 分子名称: Aspartate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H. 登録日 2002-06-14 公開日 2002-07-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis J.BIOL.CHEM., 278, 2003
1IJI	Crystal Structure of L-Histidinol Phosphate Aminotransferase with PLP 分子名称: Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Sivaraman, J, Li, Y, Larocque, R, Schrag, J.D, Cygler, M, Matte, A. 登録日 2001-04-26 公開日 2001-08-29 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate. J.Mol.Biol., 311, 2001
4FL0	Crystal structure of ALD1 from Arabidopsis thaliana 分子名称: Aminotransferase ALD1, PYRIDOXAL-5'-PHOSPHATE 著者 Sobolev, V, Edelman, M, Dym, O, Unger, T, Albeck, S, Kirma, M, Galili, G, Israel Structural Proteomics Center (ISPC) 登録日 2012-06-14 公開日 2013-02-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis. Acta Crystallogr.,Sect.F, 69, 2013
1IVR	STRUCTURE OF ASPARTATE AMINOTRANSFERASE 分子名称: ASPARTATE AMINOTRANSFERASE, N-PYRIDOXYL-2,3-DIHYDROXYASPARTIC ACID-5-MONOPHOSPHATE 著者 Graf Von Stosch, A. 登録日 1996-10-11 公開日 1997-07-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Aspartate aminotransferase complexed with erythro-beta-hydroxyaspartate: crystallographic and spectroscopic identification of the carbinolamine intermediate. Biochemistry, 35, 1996
1IX8	Aspartate Aminotransferase Active Site Mutant V39F/N194A 分子名称: Aspartate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H. 登録日 2002-06-14 公開日 2002-07-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis J.BIOL.CHEM., 278, 2003
1IX7	Aspartate Aminotransferase Active Site Mutant V39F maleate complex 分子名称: Aspartate Aminotransferase, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE 著者 Hayashi, H, Mizuguchi, H, Miyahara, I, Nakajima, Y, Hirotsu, K, Kagamiyama, H. 登録日 2002-06-14 公開日 2002-07-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis J.BIOL.CHEM., 278, 2003
4GEB	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(7-hydroxy-6-oxo-2-phenyl-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-5-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, ... 著者 Pandit, J. 登録日 2012-08-01 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency. Bioorg.Med.Chem.Lett., 23, 2013
4GE7	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-6-phenoxy-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-11-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
4GE4	Kynurenine Aminotransferase II Inhibitors 分子名称: (5-hydroxy-4-{[(1-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Pandit, J. 登録日 2012-08-01 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013

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