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4IDX
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BU of 4idx by Molmil
hexameric crystal structure of Schmallenberg virus nucleoprotein
Descriptor: Nucleocapsid protein
Authors:Dong, H, Dong, C.
Deposit date:2012-12-13
Release date:2013-04-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structure of Schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation
J.Virol., 87, 2013
4II3
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BU of 4ii3 by Molmil
Crystal structure of S. pombe Ubiquitin activating enzyme 1 (Uba1) in complex with ubiquitin and ATP/Mg
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Olsen, S.K, Lima, C.D.
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
6CKQ
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BU of 6ckq by Molmil
Solution structure of the Burkholderia thailandensis transcription antitermination protein NusB (BTH_I1529) - Seattle Structural Genomics Center for Infectious Disease target ButhA.17903.a
Descriptor: Transcription antitermination protein NusB
Authors:Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-02-28
Release date:2018-04-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the Burkholderia thailandensis transcription antitermination protein NusB (BTH_I1529).
To Be Published
2C2L
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BU of 2c2l by Molmil
Crystal structure of the CHIP U-box E3 ubiquitin ligase
Descriptor: CARBOXY TERMINUS OF HSP70-INTERACTING PROTEIN, HSP90, NICKEL (II) ION, ...
Authors:Zhang, M, Roe, S.M, Pearl, L.H.
Deposit date:2005-09-29
Release date:2005-11-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Chaperoned Ubiquitylation-Crystal Structures of the Chip U Box E3 Ubiquitin Ligase and a Chip-Ubc13-Uev1A Complex
Mol.Cell, 20, 2005
6CP2
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BU of 6cp2 by Molmil
SidC in complex with UbcH7~Ub
Descriptor: Polyubiquitin-B, SidC, Ubiquitin-conjugating enzyme E2 L3
Authors:Wasilko, D.J, Huang, Q, Mao, Y.
Deposit date:2018-03-13
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into the ubiquitin transfer cascade catalyzed by theLegionellaeffector SidC.
Elife, 7, 2018
6GE0
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BU of 6ge0 by Molmil
Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2
Descriptor: 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]ethanamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ...
Authors:O'Reilly, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.
J. Med. Chem., 61, 2018
2JWO
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BU of 2jwo by Molmil
A PHD finger motif in the C-terminus of RAG2 modulates recombination activity
Descriptor: V(D)J recombination-activating protein 2, ZINC ION
Authors:Ivanov, D, Hyberts, S.G, Sun, Z, Wagner, G.
Deposit date:2007-10-17
Release date:2007-11-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
J.Biol.Chem., 280, 2005
1FPV
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BU of 1fpv by Molmil
STRUCTURE DETERMINATION OF FELINE PANLEUKOPENIA VIRUS EMPTY PARTICLES
Descriptor: FELINE PANLEUKOPENIA VIRUS (STRAIN B) VIRAL PROTEIN 2
Authors:Agbandje, M, Rossmann, M.G.
Deposit date:1993-03-04
Release date:1994-01-31
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure determination of feline panleukopenia virus empty particles.
Proteins, 16, 1993
6GJB
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BU of 6gjb by Molmil
Erk2 signalling protein
Descriptor: Mitogen-activated protein kinase 1, SULFATE ION, [(1~{R},4~{Z})-cyclooct-4-en-1-yl] ~{N}-[4-[4-[[4-[1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate
Authors:O'Reilly, M.
Deposit date:2018-05-16
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe.
Chem Sci, 9, 2018
2NPQ
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BU of 2npq by Molmil
A Novel Lipid Binding Site in the p38 alpha MAP Kinase
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Engelberg, D, Livnah, O.
Deposit date:2006-10-29
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel lipid binding site formed by the MAP kinase insert in p38 alpha.
J.Mol.Biol., 375, 2008
4II2
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BU of 4ii2 by Molmil
Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Olsen, S.K, Lima, C.D.
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
3TVV
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BU of 3tvv by Molmil
Structure of the tandem PH domains of Rtt106 (residues 68-315)
Descriptor: Histone chaperone RTT106
Authors:Su, D, Thompson, J.R, Mer, G.
Deposit date:2011-09-20
Release date:2012-02-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
7F60
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BU of 7f60 by Molmil
Crystal structure of auxiliary protein in complex with human nuclear protein
Descriptor: Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor
Authors:Gao, X, Cui, S.
Deposit date:2021-06-23
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport
Nat Commun, 13, 2022
7F90
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BU of 7f90 by Molmil
Crystal structure of SARS auxiliary protein in complex with human nuclear protein
Descriptor: Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor
Authors:Gao, X, Cui, S.
Deposit date:2021-07-03
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport
Nat Commun, 13, 2022
2FD5
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BU of 2fd5 by Molmil
The crystal structure of a transcriptional regulator from Pseudomonas aeruginosa PAO1
Descriptor: transcriptional regulator
Authors:Zhang, R, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-12-13
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of a transcriptional regulator from Pseudomonas aeruginosa PAO1
To be Published
1JL1
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BU of 1jl1 by Molmil
D10A E. coli ribonuclease HI
Descriptor: RIBONUCLEASE HI
Authors:Goedken, E.R, Marqusee, S.
Deposit date:2001-07-13
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Native-state energetics of a thermostabilized variant of ribonuclease HI.
J.Mol.Biol., 314, 2001
7EVN
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BU of 7evn by Molmil
The cryo-EM structure of the DDX42-SF3b complex
Descriptor: ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-05-21
Release date:2022-08-03
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
1QHI
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BU of 1qhi by Molmil
HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE COMPLEXED WITH A NOVEL NON-SUBSTRATE INHIBITOR, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE
Descriptor: 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE, PROTEIN (THYMIDINE KINASE), SULFATE ION
Authors:Bennett, M.S, Wien, F, Champness, J.N, Batuwangala, T, Rutherford, T, Summers, W.C, Sun, H, Wright, G, Sanderson, M.R.
Deposit date:1999-05-12
Release date:1999-07-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir.
FEBS Lett., 443, 1999
1JXB
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BU of 1jxb by Molmil
I53A, a point mutant of the cysteine-free variant of E. coli Rnase HI
Descriptor: Ribonuclease HI
Authors:Spudich, G, Lorenz, S, Marqusee, S.
Deposit date:2001-09-06
Release date:2002-03-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.
Protein Sci., 11, 2002
1HYW
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BU of 1hyw by Molmil
SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW
Descriptor: HEAD-TO-TAIL JOINING PROTEIN W
Authors:Maxwell, K.L, Yee, A.A, Booth, V, Arrowsmith, C.H, Gold, M, Davidson, A.R.
Deposit date:2001-01-22
Release date:2001-04-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The solution structure of bacteriophage lambda protein W, a small morphogenetic protein possessing a novel fold.
J.Mol.Biol., 308, 2001
7FIK
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BU of 7fik by Molmil
The cryo-EM structure of the CR subunit from X. laevis NPC
Descriptor: MGC154553 protein, MGC83295 protein, MGC83926 protein, ...
Authors:Shi, Y, Huang, G, Zhan, X.
Deposit date:2021-07-31
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
2COB
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BU of 2cob by Molmil
Solution structures of the HTH domain of human LCoR protein
Descriptor: LCoR protein
Authors:Nameki, N, Umehara, T, Sato, M, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-17
Release date:2005-11-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the HTH domain of human LCoR protein
To be Published
1Z8V
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BU of 1z8v by Molmil
The Structure of d(GGCCAATTGG) Complexed with Netropsin
Descriptor: (5'-D(*GP*GP*CP*CP*AP*AP*TP*TP*GP*G)-3'), NETROPSIN
Authors:Van Hecke, K, Nam, P.C, Nguyen, M.T, Van Meervelt, L.
Deposit date:2005-03-31
Release date:2006-03-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations.
Febs J., 272, 2005
2ERC
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BU of 2erc by Molmil
CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE
Descriptor: RRNA METHYL TRANSFERASE
Authors:Bussiere, D.E, Muchmore, S.W, Dealwis, C.G, Schluckebier, G, Abad-Zapatero, C.
Deposit date:1998-03-13
Release date:1999-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Biochemistry, 37, 1998
3AXJ
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BU of 3axj by Molmil
High resolution crystal structure of C3PO
Descriptor: GM27569p, Translin associated factor X, isoform B
Authors:Yuan, Y.A, Yang, X.
Deposit date:2011-04-07
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High resolution crystal structure of C3PO
To be Published

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