5W98
| Pyridine synthase, PbtD, from GE2270 biosynthesis | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PbtD | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2017-06-22 | Release date: | 2017-11-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5W99
| Pyridine synthase, PbtD, from GE2270 biosynthesis bound to TSP | Descriptor: | 2,2'-(6-(2'-(aminomethyl)-[2,4'-bithiazol]-4-yl)pyridine-2,5-diyl)bis(thiazole-4-carboxylic acid), PbtD, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2017-06-22 | Release date: | 2017-11-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8EJZ
| [4+2] Aza-Cyclase Y293F variant | Descriptor: | PbtD | Authors: | Nair, S.K. | Deposit date: | 2022-09-19 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis. J.Am.Chem.Soc., 144, 2022
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8EJY
| [4+2] Aza-Cyclase F293A variant | Descriptor: | PbtD | Authors: | Nair, S.K. | Deposit date: | 2022-09-19 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis. J.Am.Chem.Soc., 144, 2022
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