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PDB: 2 results

Mucor circinelloides FKBP12 protein bound with APX879 in C2221 space group
Descriptor:	N'-[(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-1,20,21-trioxo-8-(prop-2-en-1-yl)-1,3,4,5,6,8,11,12,13,14,15,16,17,18,19,20,21,23,24,25,26,26a-docosahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosin-7-ylidene]acetohydrazide, Peptidylprolyl isomerase
Authors:	Gobeil, S, Spicer, L.
Deposit date:	2019-12-23
Release date:	2020-12-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. Mbio, 12, 2021

Mucor circinelloides FKBP12 protein bound with FK506 in P3221 space group
Descriptor:	8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Peptidylprolyl isomerase
Authors:	Gobeil, S, Spicer, L.
Deposit date:	2020-02-10
Release date:	2020-12-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.54 Å)
Cite:	Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs. Mbio, 12, 2021