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PDB: 6 results

8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Dybkov, O, Kastner, B, Luehrmann, R.
Deposit date:2023-01-12
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
6ZYM
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BU of 6zym by Molmil
Human C Complex Spliceosome - High-resolution CORE
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Corepressor interacting with RBPJ 1, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-02
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
5YZG
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BU of 5yzg by Molmil
The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y.
Deposit date:2017-12-14
Release date:2018-08-08
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of a human catalytic step I spliceosome
Science, 359, 2018
6FF7
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BU of 6ff7 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2019-03-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
7A5P
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BU of 7a5p by Molmil
Human C Complex Spliceosome - Medium-resolution PERIPHERY
Descriptor: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-21
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Cretu, C, Schmitzova, J, Pena, V.
Deposit date:2023-02-07
Release date:2023-05-10
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of catalytic activation in human splicing.
Nature, 617, 2023

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