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PDB: 11 results

2GHT
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CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2GHQ
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CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
1TA0
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Three-dimensional structure of a RNA-polymerase II binding protein with associated ligand.
Descriptor: CITRIC ACID, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Kamenski, T, Heilmeier, S, Meinhart, T, Cramer, P.
Deposit date:2004-05-19
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Mechanism of RNA Polymerase II CTD Phosphatases.
Mol.Cell, 15, 2004
4YH1
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BU of 4yh1 by Molmil
Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide
Descriptor: A small phosphatase 1, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Mayfield, J.E, Zhang, Y.
Deposit date:2015-02-26
Release date:2015-09-16
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
1T9Z
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BU of 1t9z by Molmil
Three-dimensional structure of a RNA-polymerase II binding protein.
Descriptor: CITRIC ACID, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Kamenski, T, Heilmeier, S, Meinhart, A, Cramer, P.
Deposit date:2004-05-19
Release date:2004-08-31
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Mechanism of RNA Polymerase II CTD Phosphatases.
Mol.Cell, 15, 2004
3L0Y
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Crystal structure OF SCP1 phosphatase D98A mutant
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Zhang, M, Zhang, Y.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
3PGL
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BU of 3pgl by Molmil
Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole
Descriptor: 2-[(R)-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl]-1H-benzimidazole, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Zhang, M, Cho, E.J, Burstein, G, Siegel, D, Zhang, Y.
Deposit date:2010-11-02
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor.
Acs Chem.Biol., 6, 2011
3L0B
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Crystal structure of SCP1 phosphatase D206A mutant phosphoryl-intermediate
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
Authors:Zhang, M, Zhang, Y.
Deposit date:2009-12-09
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
4YGY
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BU of 4ygy by Molmil
Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide
Authors:Mayfield, J.E, Zhang, Y.
Deposit date:2015-02-26
Release date:2015-09-16
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
3L0C
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BU of 3l0c by Molmil
Crystal structure of SCP1 phosphatase D206A mutant with trapped inorganic phosphate
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, PHOSPHATE ION
Authors:Zhang, M, Zhang, Y.
Deposit date:2009-12-09
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein Sci., 19, 2010
6DU3
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Structure of Scp1 D96N bound to REST-pS861/4 peptide
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
Authors:Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018

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