8U53
 
 | | Mechanically activated ion channel OSCA3.1 in nanodiscs | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CSC1-like protein ERD4, PALMITIC ACID, ... | | Authors: | Jojoa-Cruz, S, Lee, W.H, Ward, A.B. | | Deposit date: | 2023-09-12 | | Release date: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli.
Elife, 12, 2024
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8XW0
 | | Cryo-EM structure of OSCA3.1-GDN state | | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | | Authors: | Zhang, Y, Han, Y. | | Deposit date: | 2024-01-15 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
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8GSO
 | | AtOSCA3.1 channel extended state | | Descriptor: | CSC1-like protein ERD4 | | Authors: | Zhang, M.F. | | Deposit date: | 2022-09-06 | | Release date: | 2023-06-14 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8GRO
 | | AtOSCA3.1 contracted state | | Descriptor: | CSC1-like protein ERD4 | | Authors: | Zhang, M.F. | | Deposit date: | 2022-09-02 | | Release date: | 2023-06-14 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity.
Nat Commun, 14, 2023
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8XVY
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8XVZ
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8XRY
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8XS0
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5Z1F
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