1TCV
 
 | | Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate | | Descriptor: | ACETATE ION, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, purine-nucleoside phosphorylase | | Authors: | Pereira, H.D, Franco, G.R, Cleasby, A, Garratt, R.C. | | Deposit date: | 2004-05-21 | | Release date: | 2005-05-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis.
J.Mol.Biol., 353, 2005
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3E9R
 | | Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with adenine | | Descriptor: | ACETATE ION, ADENINE, DIMETHYL SULFOXIDE, ... | | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | | Deposit date: | 2008-08-23 | | Release date: | 2009-09-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3FNQ
 | | Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine | | Descriptor: | DIMETHYL SULFOXIDE, HYPOXANTHINE, Purine-nucleoside phosphorylase, ... | | Authors: | Castilho, M.S, Pereira, H.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-12-26 | | Release date: | 2009-02-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3FAZ
 | | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with inosine | | Descriptor: | INOSINE, Purine-nucleoside phosphorylase, SULFATE ION | | Authors: | Pereira, H.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-11-18 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3E0Q
 | | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor | | Descriptor: | 6-amino-5-bromo-1,2,3,4-tetrahydropyrimidine-2,4-dione, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase | | Authors: | Pereira, H.M, Berdini, V, Ferri, M.R, Cleasby, A, Garratt, R.C. | | Deposit date: | 2008-07-31 | | Release date: | 2009-08-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.
Acta Trop., 114, 2010
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1TD1
 | | Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with acetate | | Descriptor: | ACETATE ION, purine-nucleoside phosphorylase | | Authors: | Pereira, H.D, Franco, G.R, Cleasby, A, Garratt, R.C. | | Deposit date: | 2004-05-21 | | Release date: | 2005-05-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis.
J.Mol.Biol., 353, 2005
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1TCU
 | | Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with phosphate and acetate | | Descriptor: | ACETATE ION, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... | | Authors: | Pereira, H.D, Franco, G.R, Cleasby, A, Garratt, R.C. | | Deposit date: | 2004-05-21 | | Release date: | 2005-05-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures for the Potential Drug Target Purine Nucleoside Phosphorylase from Schistosoma mansoni Causal Agent of Schistosomiasis.
J.Mol.Biol., 353, 2005
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3FB1
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3IEX
 | | Schistosoma Purine nucleoside phosphorylase in complex with guanosine | | Descriptor: | ACETATE ION, DIMETHYL SULFOXIDE, GUANOSINE, ... | | Authors: | Castilho, M.S, Pereira, H.M, Oliva, G, Andricopulo, A.D. | | Deposit date: | 2009-07-23 | | Release date: | 2010-03-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies
Bioorg.Med.Chem., 18, 2010
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3F8W
 | | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine | | Descriptor: | ADENOSINE, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | | Authors: | Pereira, H.M, Rezende, M.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-11-13 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3DJF
 | | Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34 | | Descriptor: | 2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | | Authors: | Postigo, M.P, Pereira, H.M, Oliva, G, Andricopulo, A.D. | | Deposit date: | 2008-06-23 | | Release date: | 2009-06-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.
Bioorg.Med.Chem., 18, 2010
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3E9Z
 | | Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with 6-chloroguanine | | Descriptor: | 6-chloroguanine, ACETATE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | | Deposit date: | 2008-08-24 | | Release date: | 2009-09-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase (SmPNP) in complex with adenine, 8-aminoguanine, 8-azaguanine and 6-chloroguanine.
To be Published
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