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PDB: 11 results
1R8S
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BU of 1r8s by Molmil
ARF1[DELTA1-17]-GDP IN COMPLEX WITH A SEC7 DOMAIN CARRYING THE MUTATION OF THE CATALYTIC GLUTAMATE TO LYSINE
Descriptor: ADP-ribosylation factor 1, Arno, BETA-MERCAPTOETHANOL, ...
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2003-10-28
Release date:2004-01-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
4JXH
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BU of 4jxh by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-28
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JMI
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BU of 4jmi by Molmil
Sec7 domain of ARNO, an exchange factor, at 1.5 Angstrom resolution
Descriptor: Cytohesin-2
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
1R8M
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BU of 1r8m by Molmil
SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
Descriptor: Arno, FORMIC ACID, MANGANESE (II) ION
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2003-10-27
Release date:2004-01-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
4L5M
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BU of 4l5m by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-06-11
Release date:2013-10-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors.
J.Med.Chem., 56, 2013
1S9D
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BU of 1s9d by Molmil
ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Descriptor: 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-Ribosylation Factor 1, Arno, ...
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2004-02-04
Release date:2004-02-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Snapshots of the Mechanism and Inhibition of a Guanine Nucleotide Exchange Factor
Nature, 426, 2003
4JMO
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BU of 4jmo by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
1R8Q
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BU of 1r8q by Molmil
FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Descriptor: 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-ribosylation factor 1, Arno, ...
Authors:Renault, L, Guibert, B, Cherfils, J.
Deposit date:2003-10-28
Release date:2004-01-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
4JWL
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BU of 4jwl by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH7.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-27
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
1PBV
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BU of 1pbv by Molmil
SEC7 DOMAIN OF THE EXCHANGE FACTOR ARNO
Descriptor: ARNO
Authors:Cherfils, J, Menetrey, J, Mathieu, M, Le Bras, G, Robineau, S, Beraud-Dufour, S, Antonny, B, Chardin, P.
Deposit date:1998-01-15
Release date:1999-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Sec7 domain of the Arf exchange factor ARNO.
Nature, 392, 1998
4Z21
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BU of 4z21 by Molmil
Crystal structure of ARNO Sec7
Descriptor: 1,2-ETHANEDIOL, Cytohesin-2
Authors:Zhu, S.J, Yun, C.H.
Deposit date:2015-03-28
Release date:2016-05-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Lack of evidence that CYTH2/ARNO functions as an intracellular EGFR activator
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