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PDB: 4 results

7Z1K
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BU of 7z1k by Molmil
Crystal structure of the SPOC domain of human SHARP (SPEN) in complex with RNA polymerase II CTD heptapeptide phosphorylated on Ser5
Descriptor: Msx2-interacting protein, SER-TYR-SER-PRO-THR-SEP
Authors:Appel, L, Grishkovskaya, I, Slade, D, Djinovic-Carugo, K.
Deposit date:2022-02-24
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
1OW1
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Crystal structure of the SPOC domain of the human transcriptional corepressor, SHARP.
Descriptor: SMART/HDAC1 associated repressor protein
Authors:Schwabe, J.W, Ariyoshi, M.
Deposit date:2003-03-28
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling
Genes Dev., 17, 2003
4P6Q
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The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA Recognition Motifs
Descriptor: Msx2-interacting protein, SULFATE ION
Authors:Arieti, F, Gabus, C, Tambalo, M, Huet, T, Round, A, Thore, S.
Deposit date:2014-03-25
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.
Nucleic Acids Res., 42, 2014
2RT5
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Structural insights into the recruitment of SMRT by the co-repressor SHARP under phosphorylative regulation
Descriptor: Msx2-interacting protein, peptide from Silencing mediator of retinoic acid and thyroid hormone receptor
Authors:Mikami, S, Kanaba, T, Mishima, M.
Deposit date:2013-04-22
Release date:2013-12-04
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.
Structure, 22, 2014

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