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PDB: 4 results

7LCZ
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BU of 7lcz by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN
Descriptor: 1,2-ETHANEDIOL, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Isoform B of NAD(+) hydrolase sarm1, ...
Authors:Gu, W, Nanson, J.D, Luo, Z, Jia, X, Manik, M.K, Ve, T, Kobe, B.
Deposit date:2021-01-12
Release date:2021-03-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
7M6K
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BU of 7m6k by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with VMN
Descriptor: 3-({[(4-nitrophenyl)carbamoyl]amino}methyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium, Isoform B of NAD(+) hydrolase sarm1, SODIUM ION
Authors:Gu, W, Luo, Z, Kobe, B.
Deposit date:2021-03-25
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1.
Elife, 10, 2021
7RTC
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BU of 7rtc by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with NaMN
Descriptor: NAD(+) hydrolase sarm1, NICOTINATE MONONUCLEOTIDE
Authors:Gu, W, Ve, T, Kobe, B.
Deposit date:2021-08-13
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection.
Exp Neurol, 345, 2021
7LCY
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BU of 7lcy by Molmil
Crystal structure of the ligand-free ARM domain from Drosophila SARM1
Descriptor: Isoform B of NAD(+) hydrolase sarm1
Authors:Gu, W, Nanson, J.D, Luo, Z, McGuinness, H.Y, Manik, M.K, Jia, X, Ve, T, Kobe, B.
Deposit date:2021-01-12
Release date:2021-03-10
Last modified:2021-04-21
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021

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PDB entries from 2024-10-09

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