6MYE
 
 | | Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) | | Descriptor: | FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... | | Authors: | Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. | | Deposit date: | 2018-11-01 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
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6EEY
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2W4F
 | | CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1 | | Descriptor: | 1,2-ETHANEDIOL, PROTEIN LAP4 | | Authors: | Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U. | | Deposit date: | 2008-11-25 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
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6MS1
 | | Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC | | Descriptor: | 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog | | Authors: | How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O. | | Deposit date: | 2018-10-16 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
FEBS Lett., 593, 2019
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6MYF
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5VWI
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7QRS
 | | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | | Descriptor: | ACETATE ION, GLYCEROL, Protein Tax-1, ... | | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | | Deposit date: | 2022-01-12 | | Release date: | 2022-09-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM.
Febs J., 290, 2023
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7QS9
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7QSB
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7QS8
 | | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | | Descriptor: | Protein Tax-1, Protein scribble homolog | | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | | Deposit date: | 2022-01-13 | | Release date: | 2022-09-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM.
Febs J., 290, 2023
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8CD3
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7QTP
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7QRT
 | | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | | Descriptor: | CHLORIDE ION, Protein Tax-1, Protein scribble homolog, ... | | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M, Maddumage, J.C. | | Deposit date: | 2022-01-12 | | Release date: | 2022-09-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM.
Febs J., 290, 2023
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5VWC
 | | Crystal structure of human Scribble PDZ1 domain | | Descriptor: | 1,2-ETHANEDIOL, Protein scribble homolog | | Authors: | Lim, K.Y.B, Kvansakul, M. | | Deposit date: | 2017-05-21 | | Release date: | 2017-11-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.911 Å) | | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
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6XA6
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8B87
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7QSA
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6MTU
 | | Crystal structure of human Scribble PDZ1:pMCC complex | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... | | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | | Deposit date: | 2018-10-22 | | Release date: | 2019-08-14 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.141 Å) | | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
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6XA8
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5VWK
 | | Crystal structure of human Scribble PDZ1:Beta-PIX complex | | Descriptor: | Beta-PIX, Protein scribble homolog, SULFATE ION | | Authors: | Lim, K.Y.B, Kvansakul, M. | | Deposit date: | 2017-05-22 | | Release date: | 2017-11-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
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8BIA
 | | Crystal structure of Scribble PDZ1 with PTHR | | Descriptor: | PHOSPHATE ION, Parathyroid hormone/parathyroid hormone-related peptide receptor, Protein scribble homolog | | Authors: | Stewart, B.Z, Kvansakul, M. | | Deposit date: | 2022-11-02 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Scribble PDZ1 with human papillomavirus strain 16 E6 peptide
To Be Published
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7JO7
 | | Crystal Structure of Human Scribble PDZ2 | | Descriptor: | 1,2-ETHANEDIOL, Protein scribble homolog | | Authors: | How, J.Y, Kvansakul, M. | | Deposit date: | 2020-08-06 | | Release date: | 2021-03-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
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4WYU
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6XA7
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8B9T
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