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PDB: 2 results

6U8Z
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BU of 6u8z by Molmil
Crystal Structure of Catalytic Domain of Human Phospholipase D1
Descriptor: PHOSPHITE ION, Phospholipase D1,Phospholipase D1
Authors:Bowling, F.Z, Airola, M.V.
Deposit date:2019-09-06
Release date:2020-03-18
Last modified:2020-04-01
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2and RhoA.
Nat.Chem.Biol., 16, 2020
6OHR
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BU of 6ohr by Molmil
Structure of compound 5 bound human Phospholipase D1 catalytic domain
Descriptor: 4-fluoro-N-{(2S)-1-[(5R)-5-(3-fluorophenyl)-2-oxo-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl]propan-2-yl}benzamide, Phospholipase D1, chimeric constuct
Authors:Metrick, C.M, Chodaparambil, J.V.
Deposit date:2019-04-06
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Human PLD structures enable drug design and characterization of isoenzyme selectivity.
Nat.Chem.Biol., 16, 2020

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