4DZD
 
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1WJ9
 | | Crystal structure of a CRISPR-associated protein from thermus thermophilus | | Descriptor: | CRISPR-associated protein | | Authors: | Ebihara, A, Yao, M, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-29 | | Release date: | 2004-11-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of hypothetical protein TTHB192 from Thermus thermophilus HB8 reveals a new protein family with an RNA recognition motif-like domain
Protein Sci., 15, 2006
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2Y9H
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2Y8W
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2Y8Y
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3QRR
 | | Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex | | Descriptor: | Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*(23G))-3') | | Authors: | Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M. | | Deposit date: | 2011-02-18 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.099 Å) | | Cite: | Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
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3QRP
 | | Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product mimic complex | | Descriptor: | Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*(PGP))-3'), RNA (5'-R(P*(U5P)P*GP*UP*GP*GP*GP*G)-3'), ... | | Authors: | Schellenberg, M.J, Gesner, E.M, Garside, E.L, MacMillan, A.M. | | Deposit date: | 2011-02-18 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.352 Å) | | Cite: | Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
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3QRQ
 | | Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex | | Descriptor: | Putative uncharacterized protein TTHB192, RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*GP*A)-3') | | Authors: | Schellenberg, M.J, Gesner, E.G, Garside, E.L, MacMillan, A.M. | | Deposit date: | 2011-02-18 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.194 Å) | | Cite: | Recognition and maturation of effector RNAs in a CRISPR interference pathway.
Nat.Struct.Mol.Biol., 18, 2011
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5CD4
 | | The Type IE CRISPR Cascade complex from E. coli, with two assemblies in the asymmetric unit arranged back-to-back | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B. | | Deposit date: | 2015-07-03 | | Release date: | 2015-08-26 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
Nucleic Acids Res., 43, 2015
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6C66
 | | CRISPR RNA-guided surveillance complex, pre-nicking | | Descriptor: | CRISPR-associated helicase, Cas3 family, CRISPR-associated protein, ... | | Authors: | Xiao, Y, Luo, M, Liao, M, Ke, A. | | Deposit date: | 2018-01-17 | | Release date: | 2018-06-27 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Science, 361, 2018
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5U07
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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5H9E
 | | Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target (32-nt spacer) at 3.20 angstrom resolution. | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | | Deposit date: | 2015-12-28 | | Release date: | 2016-02-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
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5H9F
 | | Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution. | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | | Deposit date: | 2015-12-28 | | Release date: | 2016-02-17 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli.
Nature, 530, 2016
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5U0A
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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4QYZ
 | | Crystal structure of a CRISPR RNA-guided surveillance complex, Cascade, bound to a ssDNA target | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Mulepati, S, Bailey, S. | | Deposit date: | 2014-07-26 | | Release date: | 2014-09-03 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.0303 Å) | | Cite: | Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target.
Science, 345, 2014
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4TVX
 | | Crystal structure of the E. coli CRISPR RNA-guided surveillance complex, Cascade | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Jackson, R.N, Golden, S.M, Carter, J, Wiedenheft, B. | | Deposit date: | 2014-06-28 | | Release date: | 2014-08-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
Science, 345, 2014
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4U7U
 | | Crystal structure of RNA-guided immune Cascade complex from E.coli | | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | | Authors: | Zhao, H, Sheng, G, Wang, J, Wang, M, Bunkoczi, G, Gong, W, Wei, Z, Wang, Y. | | Deposit date: | 2014-07-31 | | Release date: | 2014-08-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
Nature, 515, 2014
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9JXS
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8YB6
 | | Type I-EHNH Cascade complex | | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | | Authors: | Li, Z. | | Deposit date: | 2024-02-11 | | Release date: | 2024-07-31 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems.
Mol.Cell, 84, 2024
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8YHA
 | | Type I-EHNH Cascade-ssDNA complex | | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | | Authors: | Li, Z. | | Deposit date: | 2024-02-27 | | Release date: | 2024-07-31 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems.
Mol.Cell, 84, 2024
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8ZLU
 | | Cryo-EM strcuture of Cas5-HNH Cascade,Conf1 | | Descriptor: | CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, CRISPR-associated endoribonuclease Cse3, ... | | Authors: | Liu, Y.N, Wang, L, Zhang, H, Zhu, H. | | Deposit date: | 2024-05-21 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (2.47 Å) | | Cite: | Cryo-EM structure of Cas5-HNH Cascade,Conf1
To Be Published
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8ZP7
 | | Cryo-EM structure of Cas5-HNH Cascade bound with sDNA, Conf1 | | Descriptor: | CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, CRISPR-associated endoribonuclease Cse3, ... | | Authors: | Liu, Y.N, Wang, L, Zhang, H, Zhu, H. | | Deposit date: | 2024-05-29 | | Release date: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structure of Cas5-HNH Cascade bound with sDNA, Conf1
To Be Published
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8ZM3
 | | Cryo-EM strcuture of Cas5-HNH Cascade,apo-Conf2 | | Descriptor: | CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, CRISPR-associated endoribonuclease Cse3, ... | | Authors: | Liu, Y.N, Wang, L, Zhang, H, Zhu, H. | | Deposit date: | 2024-05-22 | | Release date: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of Cas5-HNH Cascade,apo-Conf2
To Be Published
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8ZOL
 | | Cryo-EM strcuture of Cas5-HNH Cascade,Conf3 | | Descriptor: | CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, CRISPR-associated endoribonuclease Cse3, ... | | Authors: | Liu, Y.N, Wang, L, Zhang, H, Zhu, H. | | Deposit date: | 2024-05-28 | | Release date: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Cryo-EM structure of Cas5-HNH Cascade,Conf3
To Be Published
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