9FDF
 
 | | Human phosphoglycerate kinase in with mixture of products and substrates produced by cross-soaking a TSA crystal | | Descriptor: | 1,3-BISPHOSPHOGLYCERIC ACID, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Cliff, M.J, Waltho, J.P, Bowler, M.W, Baxter, N.J, Bisson, C, Blackburn, G.M. | | Deposit date: | 2024-05-16 | | Release date: | 2025-10-29 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | The role of magnesium in catalysis by phosphoglycerate kinase
To be published
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7ZY7
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2ZGV
 | | Crystal Structure of human phosphoglycerate kinase bound to D-ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphoglycerate kinase 1 | | Authors: | Arold, S.T, Gondeau, C, Lionne, C, Chaloin, L. | | Deposit date: | 2008-01-26 | | Release date: | 2008-07-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase
Nucleic Acids Res., 36, 2008
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1QPG
 | | 3-PHOSPHOGLYCERATE KINASE, MUTATION R65Q | | Descriptor: | 3-PHOSPHOGLYCERATE KINASE, 3-PHOSPHOGLYCERIC ACID, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE | | Authors: | Mcphillips, T.M, Hsu, B.T, Sherman, M.A, Mas, M.T, Rees, D.C. | | Deposit date: | 1996-01-04 | | Release date: | 1996-06-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the R65Q mutant of yeast 3-phosphoglycerate kinase complexed with Mg-AMP-PNP and 3-phospho-D-glycerate.
Biochemistry, 35, 1996
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5BT8
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9KER
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8YHP
 | | Structure of the PGK1 from Biortus. | | Descriptor: | 1,2-ETHANEDIOL, Phosphoglycerate kinase 1 | | Authors: | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | | Deposit date: | 2024-02-28 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of the PGK1 from Biortus.
To Be Published
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2CUN
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7LA1
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1PHP
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3UWD
 | | Crystal Structure of Phosphoglycerate Kinase from Bacillus Anthracis | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Zheng, H, Chruszcz, M, Porebski, P, Kudritska, M, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-12-01 | | Release date: | 2012-01-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.
J.Struct.Funct.Genom., 13, 2012
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2IE8
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1V6S
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5O7D
 | | The X-ray structure of human R38M phosphoglycerate kinase 1 mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosphoglycerate kinase 1 | | Authors: | Ilari, A, Fiorillo, A, Cipollone, A, Petrosino, M. | | Deposit date: | 2017-06-08 | | Release date: | 2018-06-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS ONE, 13, 2018
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13PK
 | | TERNARY COMPLEX OF PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI | | Descriptor: | 3-PHOSPHOGLYCERATE KINASE, 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Bernstein, B.E, Michels, P.A.M, Hol, W.G.J. | | Deposit date: | 1996-11-23 | | Release date: | 1997-12-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation.
Nature, 385, 1997
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6HXE
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5NP8
 | | PGK1 in complex with CRT0063465 (3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid) | | Descriptor: | 1,2-ETHANEDIOL, 3-PHOSPHOGLYCERIC ACID, 3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid, ... | | Authors: | Turnbull, A.P, Bilsland, A.E, Liu, Y, Sumpton, D, Stevenson, K, Cairney, C.J, Roffey, J, Jenkinson, D, Keith, W.N. | | Deposit date: | 2017-04-13 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation.
Neoplasia, 21, 2019
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1FW8
 | | CIRCULARLY PERMUTED PHOSPHOGLYCERATE KINASE FROM YEAST: PGK P72 | | Descriptor: | GLYCEROL, Phosphoglycerate kinase | | Authors: | Tougard, P, Bizebard, T, Ritco-Vonsovici, M, Minard, P, Desmadril, M. | | Deposit date: | 2000-09-22 | | Release date: | 2001-03-22 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a circularly permuted phosphoglycerate kinase.
Acta Crystallogr.,Sect.D, 58, 2002
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1KF0
 | | Crystal Structure of Pig Muscle Phosphoglycerate Kinase Ternary Complex with AMP-PCP and 3PG | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | Authors: | Kovari, Z, Flachner, B, Naray-Szabo, G, Vas, M. | | Deposit date: | 2001-11-19 | | Release date: | 2002-07-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic and thiol-reactivity studies on the complex of pig muscle phosphoglycerate kinase with ATP analogues: correlation between nucleotide binding mode and helix flexibility.
Biochemistry, 41, 2002
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1HDI
 | | Pig muscle 3-PHOSPHOGLYCERATE KINASE complexed with 3-PG and MgADP. | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Szilagyi, A.N, Ghosh, M, Garman, E, Vas, M. | | Deposit date: | 2000-11-16 | | Release date: | 2001-02-26 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A 1.8 A resolution structure of pig muscle 3-phosphoglycerate kinase with bound MgADP and 3-phosphoglycerate in open conformation: new insight into the role of the nucleotide in domain closure.
J. Mol. Biol., 306, 2001
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6I06
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16PK
 | | PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI BISUBSTRATE ANALOG | | Descriptor: | 1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE ESTER, 3-PHOSPHOGLYCERATE KINASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | | Authors: | Bernstein, B.E, Bressi, J, Blackburn, M, Gelb, M, Hol, W.G.J. | | Deposit date: | 1998-05-18 | | Release date: | 1998-11-25 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei.
J.Mol.Biol., 279, 1998
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1LTK
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9FDN
 | | Human phosphoglycerate kinase in complex with ATP and 3PG formed by cross-soaking a TSA crystal | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Phosphoglycerate kinase 1, ... | | Authors: | Cliff, M.J, Waltho, J.P, Bowler, M.W, Baxter, N.J, Bisson, C, Blackburn, G.M. | | Deposit date: | 2024-05-17 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | The role of magnesium in catalysis by phosphoglycerate kinase
To be published
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9FDH
 | | Closed Human phosphoglycerate kinase complex with BPG and ADP produced by cross-soaking a TSA crystal | | Descriptor: | 1,3-BISPHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | Authors: | Cliff, M.J, Waltho, J.P, Bowler, M.W, Baxter, N.J, Bisson, C, Blackburn, G.M. | | Deposit date: | 2024-05-17 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (1.756 Å) | | Cite: | The role of magnesium in catalysis by phosphoglycerate kinase
To be published
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