4EPU
 
 | | Ang1 fibrinogen-related domain (FReD) | | Descriptor: | Angiopoietin-1, CALCIUM ION | | Authors: | Yeykal, C.C, Adams, E.J. | | Deposit date: | 2012-04-17 | | Release date: | 2013-04-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Biochemical and structural characterization of the Ang1 fibrinogen-related domain
To be Published
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4WN0
 | | Xenopus laevis embryonic epidermal lectin in complex with glycerol phosphate | | Descriptor: | CALCIUM ION, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ... | | Authors: | Wangkanont, K, Kiessling, L.L, Forest, K.T. | | Deposit date: | 2014-10-10 | | Release date: | 2016-01-20 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.
J.Biol.Chem., 291, 2016
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6QNV
 | | Fibrinogen-like globe domain of Human Tenascin-C | | Descriptor: | Tenascin | | Authors: | Coker, J.A, Bezerra, G.A, Bradshaw, W.J, Zhang, M, Yosaatmadja, Y, Fernandez-Cid, A, Shrestha, L, Burgess-Brown, N, Gileadi, O, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-02-12 | | Release date: | 2019-02-27 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Fibrinogen-like globe domain of Human Tenascin-C
To Be Published
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7TZ2
 | | Structure of human Fibrinogen-like protein 1 | | Descriptor: | CALCIUM ION, Fibrinogen-like protein 1 | | Authors: | Ming, Q, Tran, T.H, Luca, V.C. | | Deposit date: | 2022-02-15 | | Release date: | 2022-05-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
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5ZC0
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7E1E
 | | Lamprey serum virus-like lectin-LSVL | | Descriptor: | CALCIUM ION, Serum lectin | | Authors: | Peng, Y. | | Deposit date: | 2021-02-01 | | Release date: | 2022-10-19 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | Structure of lamprey serum virus-like lectin with high binding capacity, involved in initiation and regulation of innate immunity
To Be Published
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7ZMK
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1Z3U
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9Q35
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9R5Y
 | | Crystal structure of the C-terminal domain of human TNC in complex with Adhiron 52 | | Descriptor: | Adhiron, Tenascin | | Authors: | Gaule, T.G, Trinh, C, Simmons, K.J, Tomlinson, D.C, Maqbool, A. | | Deposit date: | 2025-05-11 | | Release date: | 2025-06-18 | | Last modified: | 2025-12-10 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Targeting Tenascin-C-Toll-like Receptor 4 signalling with Adhiron-derived small molecules - a viable strategy for reducing fibrosis in systemic sclerosis.
Bioorg.Chem., 167, 2025
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6Y41
 | | Fibrinogen-like globe domain of human ANGPTL2 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Angiopoietin-related protein 2, ... | | Authors: | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-02-19 | | Release date: | 2020-03-04 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Fibrinogen-like globe domain of human ANGPTL2
To Be Published
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6Y43
 | | Fibrinogen-like globe domain of human ANGPTL6 | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Angiopoietin-related protein 6, ... | | Authors: | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-02-19 | | Release date: | 2020-03-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Fibrinogen-like globe domain of human ANGPTL6
To Be Published
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8UN7
 | | Single particle analysis of recombinant human MFAP4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Microfibril-associated glycoprotein 4 | | Authors: | Wozny, M.W, Nelea, V. | | Deposit date: | 2023-10-18 | | Release date: | 2024-05-22 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Microfibril-associated glycoprotein 4 forms octamers that mediate interactions with elastogenic proteins and cells.
Nat Commun, 15, 2024
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4R9T
 | | L-ficolin complexed to sulphates | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | Authors: | Laffly, E, Lacroix, M, Martin, L, Vassal-Stermann, E, Thielens, N, Gaboriaud, C. | | Deposit date: | 2014-09-08 | | Release date: | 2014-11-05 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Human ficolin-2 recognition versatility extended: An update on the binding of ficolin-2 to sulfated/phosphated carbohydrates.
Febs Lett., 588, 2014
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4WMO
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1Z3S
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8VGP
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4ZFG
 | | Dual-specificity Fab 5A12 in complex with Angiopoietin 2 | | Descriptor: | Angiopoietin-2, CALCIUM ION, Fragment antigen binding 5A12 heavy chain, ... | | Authors: | Harris, S.F, Wu, P. | | Deposit date: | 2015-04-21 | | Release date: | 2015-07-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
J.Biol.Chem., 290, 2015
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6EUA
 | | The fibrinogen-like domain of human Angptl3 | | Descriptor: | Angiopoietin-related protein 3 | | Authors: | Biterova, E.I, Esmaeeli, M.E, Alanen, H.I, Saaranen, M, Ruddock, L.W. | | Deposit date: | 2017-10-30 | | Release date: | 2018-05-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease.
Sci Rep, 8, 2018
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4R9J
 | | L-ficolin complexed to glucosamine-6-sulfate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, ACETATE ION, ... | | Authors: | Laffly, E, Lacroix, M, Martin, L, Vassal-Stermann, E, Thielens, N, Gaboriaud, C. | | Deposit date: | 2014-09-05 | | Release date: | 2014-11-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Human ficolin-2 recognition versatility extended: An update on the binding of ficolin-2 to sulfated/phosphated carbohydrates.
Febs Lett., 588, 2014
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6EUB
 | | The fibrinogen-like domain of human Angptl4 | | Descriptor: | Angiopoietin-related protein 4, PENTAETHYLENE GLYCOL | | Authors: | Biterova, E.I, Esmaeeli, M, Alanen, H.I, Saaranen, M, Ruddock, L.W. | | Deposit date: | 2017-10-30 | | Release date: | 2018-05-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease.
Sci Rep, 8, 2018
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2D39
 | | Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain | | Descriptor: | CALCIUM ION, Ficolin-1 | | Authors: | Tanio, M, Kondo, S, Sugio, S, Kohno, T. | | Deposit date: | 2005-09-26 | | Release date: | 2006-12-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Trivalent recognition unit of innate immunity system; crystal structure of trimeric human m-ficolin fibrinogen-like domain
J.Biol.Chem., 282, 2007
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4M7F
 | | Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with bound ManNAc | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Shrive, A.K, Greenhough, T.J, Holmskov, U. | | Deposit date: | 2013-08-12 | | Release date: | 2013-12-11 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein.
J.Biol.Chem., 289, 2014
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4M7H
 | | Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ... | | Authors: | Shrive, A.K, Greenhough, T.J, Holmskov, U. | | Deposit date: | 2013-08-12 | | Release date: | 2013-12-11 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein.
J.Biol.Chem., 289, 2014
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6U73
 | | Human Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) with Myristic Acid | | Descriptor: | Angiopoietin-related protein 4, MYRISTIC ACID | | Authors: | Tarver, C.L, Yuan, Q, Singhal, A.J, Ramaker, R, Cooper, S, Pusey, M.L. | | Deposit date: | 2019-08-31 | | Release date: | 2019-10-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Crystal Structures of Angiopoietin-Like 4s C-Terminal Domain (cANGPTL4) Reveal a Binding Site for Various Ligands
To Be Published
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