5EE5
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![BU of 5ee5 by Molmil](/molmil-images/mine/5ee5) | Structure of human ARL1 in complex with the DCB domain of BIG1 | Descriptor: | ACETATE ION, ADP-ribosylation factor-like protein 1, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, ... | Authors: | Galindo, A, Soler, N, Munro, S. | Deposit date: | 2015-10-22 | Release date: | 2016-07-06 | Last modified: | 2016-07-27 | Method: | X-RAY DIFFRACTION (2.279 Å) | Cite: | Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi. Cell Rep, 16, 2016
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7OK7
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![BU of 7ok7 by Molmil](/molmil-images/mine/7ok7) | Crystal structure of the UNC119B ARL3 complex | Descriptor: | 1,2-ETHANEDIOL, ADP-ribosylation factor-like protein 3, GLYCEROL, ... | Authors: | Yelland, T, Ismail, S. | Deposit date: | 2021-05-17 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms. Biochemistry, 60, 2021
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7MGE
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![BU of 7mge by Molmil](/molmil-images/mine/7mge) | Structure of C9orf72:SMCR8:WDR41 in complex with ARF1 | Descriptor: | ADP-ribosylation factor 1, BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Su, M.-Y, Hurley, J.H. | Deposit date: | 2021-04-12 | Release date: | 2021-06-23 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Structural basis for the ARF GAP activity and specificity of the C9orf72 complex. Nat Commun, 12, 2021
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2QTV
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![BU of 2qtv by Molmil](/molmil-images/mine/2qtv) | Structure of Sec23-Sar1 complexed with the active fragment of Sec31 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein transport protein SEC23, ... | Authors: | Goldberg, J, Bi, X, Mancias, J.D. | Deposit date: | 2007-08-02 | Release date: | 2008-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. Dev.Cell, 13, 2007
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6X90
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![BU of 6x90 by Molmil](/molmil-images/mine/6x90) | |
7DN9
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![BU of 7dn9 by Molmil](/molmil-images/mine/7dn9) | |
7DN8
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![BU of 7dn8 by Molmil](/molmil-images/mine/7dn8) | Crystal structure of Salmonella effector SopF in complex with ARF1 | Descriptor: | ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ding, J, Shao, F. | Deposit date: | 2020-12-09 | Release date: | 2021-12-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6084 Å) | Cite: | ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy. Nat.Struct.Mol.Biol., 29, 2022
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2W83
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![BU of 2w83 by Molmil](/molmil-images/mine/2w83) | Crystal structure of the ARF6 GTPase in complex with a specific effector, JIP4 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ADP-RIBOSYLATION FACTOR 6, C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4, ... | Authors: | Isabet, T, Montagnac, G, Regazzoni, K, Raynal, B, El Khadali, F, Franco, M, England, P, Chavrier, P, Houdusse, A, Menetrey, J. | Deposit date: | 2009-01-08 | Release date: | 2009-07-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The Structural Basis of Arf Effector Specificity: The Crystal Structure of Arf6 in a Complex with Jip4. Embo J., 28, 2009
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3DOF
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![BU of 3dof by Molmil](/molmil-images/mine/3dof) | Complex of ARL2 and BART, Crystal Form 2 | Descriptor: | ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhang, T, Li, S, Ding, J. | Deposit date: | 2008-07-04 | Release date: | 2009-03-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector Structure, 17, 2009
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6ZGA
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![BU of 6zga by Molmil](/molmil-images/mine/6zga) | COPII on membranes, inner coat | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PRO-PRO-PRO, ... | Authors: | Zanetti, G, Hutchings, J, Cheung, A.C.M. | Deposit date: | 2020-06-18 | Release date: | 2021-02-17 | Last modified: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network. Nat Commun, 12, 2021
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7URO
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![BU of 7uro by Molmil](/molmil-images/mine/7uro) | |
7R4H
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![BU of 7r4h by Molmil](/molmil-images/mine/7r4h) | phospho-STING binding to adaptor protein complex-1 | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Xu, P, Ablasser, A. | Deposit date: | 2022-02-08 | Release date: | 2022-09-14 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Clathrin-associated AP-1 controls termination of STING signalling. Nature, 610, 2022
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7UX3
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![BU of 7ux3 by Molmil](/molmil-images/mine/7ux3) | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | Authors: | Hooy, R.M, Hurley, J.H. | Deposit date: | 2022-05-04 | Release date: | 2023-05-10 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat. Sci Adv, 8, 2022
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5NZS
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![BU of 5nzs by Molmil](/molmil-images/mine/5nzs) | The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor | Descriptor: | ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | Deposit date: | 2017-05-15 | Release date: | 2017-06-28 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (10.1 Å) | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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5NZR
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![BU of 5nzr by Molmil](/molmil-images/mine/5nzr) | The structure of the COPI coat leaf | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | Deposit date: | 2017-05-15 | Release date: | 2017-06-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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3LVQ
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![BU of 3lvq by Molmil](/molmil-images/mine/3lvq) | The crystal structure of ASAP3 in complex with Arf6 in transition state | Descriptor: | ALUMINUM FLUORIDE, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, ... | Authors: | Ismail, S.A, Vetter, I.R, Sot, B, Wittinghofer, A. | Deposit date: | 2010-02-22 | Release date: | 2010-06-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism Cell(Cambridge,Mass.), 141, 2010
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1R8S
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![BU of 1r8s by Molmil](/molmil-images/mine/1r8s) | ARF1[DELTA1-17]-GDP IN COMPLEX WITH A SEC7 DOMAIN CARRYING THE MUTATION OF THE CATALYTIC GLUTAMATE TO LYSINE | Descriptor: | ADP-ribosylation factor 1, Arno, BETA-MERCAPTOETHANOL, ... | Authors: | Renault, L, Guibert, B, Cherfils, J. | Deposit date: | 2003-10-28 | Release date: | 2004-01-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor Nature, 426, 2003
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3DOE
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![BU of 3doe by Molmil](/molmil-images/mine/3doe) | Complex of ARL2 and BART, Crystal Form 1 | Descriptor: | ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhang, T, Li, S, Ding, J. | Deposit date: | 2008-07-04 | Release date: | 2009-03-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector Structure, 17, 2009
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3VHX
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![BU of 3vhx by Molmil](/molmil-images/mine/3vhx) | The crystal structure of Arf6-MKLP1 (Mitotic kinesin-like protein 1) complex | Descriptor: | ADP-ribosylation factor 6, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Makyio, H, Takei, T, Ohgi, H, Takahashi, S, Takatsu, H, Ueda, T, Kanaho, Y, Xie, Y, Shin, H.W, Kamikubo, H, Kataoka, M, Kawasaki, M, Kato, R, Wakatsuki, S, Nakayama, K. | Deposit date: | 2011-09-12 | Release date: | 2012-05-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis Embo J., 31, 2012
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3O47
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![BU of 3o47 by Molmil](/molmil-images/mine/3o47) | Crystal structure of ARFGAP1-ARF1 fusion protein | Descriptor: | ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, H, Tong, Y, Nedyalkova, L, Tempel, W, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-07-26 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of ARFGAP1-ARF1 fusion protein to be published
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6VBV
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![BU of 6vbv by Molmil](/molmil-images/mine/6vbv) | Structure of the bovine BBSome:ARL6:GTP complex | Descriptor: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | Authors: | Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. | Deposit date: | 2019-12-19 | Release date: | 2020-01-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and activation mechanism of the BBSome membrane protein trafficking complex. Elife, 9, 2020
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6VOA
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![BU of 6voa by Molmil](/molmil-images/mine/6voa) | Cryo-EM structure of the BBSome-ARL6 complex | Descriptor: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | Authors: | Yang, S, Walz, T, Nachury, M.V. | Deposit date: | 2020-01-30 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife, 9, 2020
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4DCN
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![BU of 4dcn by Molmil](/molmil-images/mine/4dcn) | Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1 | Descriptor: | ADP-ribosylation factor-like protein 1, Arfaptin-2, MAGNESIUM ION, ... | Authors: | Nakamura, K, Xie, Y, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-01-18 | Release date: | 2012-06-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase J.Biol.Chem., 287, 2012
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5NZT
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![BU of 5nzt by Molmil](/molmil-images/mine/5nzt) | The structure of the COPI coat linkage I | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | Deposit date: | 2017-05-15 | Release date: | 2017-06-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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5NZV
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![BU of 5nzv by Molmil](/molmil-images/mine/5nzv) | The structure of the COPI coat linkage IV | Descriptor: | ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... | Authors: | Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. | Deposit date: | 2017-05-15 | Release date: | 2017-06-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (17.299999 Å) | Cite: | 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
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