7QCR
| MLLT4/Afadin PDZ domain in complex with the C-terminal peptide from protein E of SARS-CoV-2 | Descriptor: | Afadin, Envelope small membrane protein, SULFATE ION | Authors: | Zhu, Y, Alvarez, F, Haouz, A, Mechaly, A, Caillet-Saguy, C. | Deposit date: | 2021-11-25 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins. Front Microbiol, 13, 2022
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5A6C
| Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation | Descriptor: | G-PROTEIN-SIGNALING MODULATOR 2, AFADIN, SULFATE ION | Authors: | Carminati, M, Gallini, S, Pirovano, L, Alfieri, A, Bisi, S, Mapelli, M. | Deposit date: | 2015-06-25 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | Concomitant Binding of Afadin to Lgn and F-Actin Directs Planar Spindle Orientation. Nat.Struct.Mol.Biol., 23, 2016
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1T2M
| Solution Structure Of The Pdz Domain Of AF-6 | Descriptor: | AF-6 protein | Authors: | Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y. | Deposit date: | 2004-04-22 | Release date: | 2005-02-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr J.Biol.Chem., 280, 2005
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2AIN
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1XZ9
| Structure of AF-6 PDZ domain | Descriptor: | Afadin | Authors: | Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H. | Deposit date: | 2004-11-12 | Release date: | 2005-11-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
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2EXG
| Making Protein-Protein Interactions Drugable: Discovery of Low-Molecular-Weight Ligands for the AF6 PDZ Domain | Descriptor: | (5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE, Afadin | Authors: | Joshi, M, Vargas, C, Boisguerin, P, Krause, G, Schade, M, Oschkinat, H. | Deposit date: | 2005-11-08 | Release date: | 2006-10-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
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