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PDB: 13 results

7S7J
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BU of 7s7j by Molmil
Structure of Human SPASTIN-IST1 complex.
Descriptor: CALCIUM ION, CHLORIDE ION, IST1 homolog, ...
Authors:Skalicky, J.J, Sundquist, W.I.
Deposit date:2021-09-16
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission.
Elife, 11, 2022
4WZX
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BU of 4wzx by Molmil
ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins
Descriptor: COBALT (II) ION, IST1 homolog, SULFATE ION, ...
Authors:Caballe, A, Wenzel, D.M, Agromayor, M, Alam, S.L, Skalicky, J.J, Kloc, M, Carlton, J.G, Labrador, L, Sundquist, W.I, Martin-Serrano, J.
Deposit date:2014-11-20
Release date:2015-06-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3859 Å)
Cite:ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
Elife, 4, 2015
4U7E
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BU of 4u7e by Molmil
The crystal structure of the complex of LIP5 NTD and IST1 MIM
Descriptor: IST1 homolog, Vacuolar protein sorting-associated protein VTA1 homolog
Authors:Guo, E.Z, Xu, Z.
Deposit date:2014-07-30
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
4U7I
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Structure of the complex of Spartin MIT and IST1 MIM
Descriptor: IST1 homolog, Spartin
Authors:Guo, E.Z, Xu, Z.
Deposit date:2014-07-30
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
3FRR
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BU of 3frr by Molmil
Structure of human IST1(NTD) - (residues 1-189)(P21)
Descriptor: Uncharacterized protein KIAA0174
Authors:Schubert, H.L, Hill, C.P, Bajorek, M, Sundquist, W.I.
Deposit date:2009-01-08
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
4U7Y
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BU of 4u7y by Molmil
Structure of the complex of VPS4B MIT and IST1 MIM
Descriptor: IST1 homolog, Vacuolar protein sorting-associated protein 4B
Authors:Guo, E.Z, Xu, Z.
Deposit date:2014-07-31
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
3FRS
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BU of 3frs by Molmil
Structure of human IST1(NTD) (residues 1-189)(p43212)
Descriptor: GLYCEROL, Uncharacterized protein KIAA0174
Authors:Schubert, H.L, Hill, C.P, Bajorek, M, Sundquist, W.I.
Deposit date:2009-01-08
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
8UC6
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BU of 8uc6 by Molmil
Calpain-7:IST1 Complex
Descriptor: Calpain-7, IST1 homolog
Authors:Paine, E, Whitby, F.G, Hill, C.P, Sunquist, W.I.
Deposit date:2023-09-25
Release date:2023-10-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission.
Elife, 12, 2023
6E8G
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BU of 6e8g by Molmil
CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Talledge, N, Frost, A, McCullough, J.
Deposit date:2018-07-29
Release date:2018-08-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
6TZ5
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BU of 6tz5 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (left-handed)
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ4
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BU of 6tz4 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed)
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
3JC1
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BU of 3jc1 by Molmil
Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer
Descriptor: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1)
Authors:McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A.
Deposit date:2015-11-09
Release date:2015-12-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
6TZA
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BU of 6tza by Molmil
CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant
Descriptor: IST1 homolog
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-11
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020

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