2QQ9
| Crystal Structure of DtxR(D6A C102D) Complexed with Nickel(II) | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | Deposit date: | 2007-07-26 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR. Biochemistry, 46, 2007
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3GLX
| Crystal Structure Analysis of the DtxR(E175K) complexed with Ni(II) | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | Authors: | D'Aquino, J.A, Denninger, A, Moulin, A, D'Aquino, K.E, Ringe, D. | Deposit date: | 2009-03-12 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Decreased sensitivity to changes in the concentration of metal ions as the basis for the hyperactivity of DtxR(E175K). J.Mol.Biol., 390, 2009
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2DTR
| STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | Authors: | Qiu, X, Pohl, E, Hol, W.G. | Deposit date: | 1996-07-26 | Release date: | 1997-08-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor. Biochemistry, 35, 1996
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2QQB
| Crystal Structure of DtxR(M10A C102D) Complexed with Nickel(II) | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | Deposit date: | 2007-07-26 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR. Biochemistry, 46, 2007
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1XCV
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1P92
| Crystal Structure of (H79A)DtxR | Descriptor: | BETA-MERCAPTOETHANOL, Diphtheria toxin repressor | Authors: | D'Aquino, J.A, Ringe, D. | Deposit date: | 2003-05-08 | Release date: | 2004-05-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Determinants of the SRC homology domain 3-like fold. J.Bacteriol., 185, 2003
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2QQA
| Crystal Structure of DtxR(E9A C102D) Complexed with Nickel(II) | Descriptor: | Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION | Authors: | D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D. | Deposit date: | 2007-07-26 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR. Biochemistry, 46, 2007
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1BI1
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1FWZ
| GLU20ALA DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-09-25 | Release date: | 2001-09-25 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1BI0
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G. | Deposit date: | 1998-06-21 | Release date: | 1999-07-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1BI2
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1G3T
| CYS102SER DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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2TDX
| DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL | Descriptor: | DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | Authors: | White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R. | Deposit date: | 1998-06-22 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature, 394, 1998
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1G3S
| CYS102SER DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1G3W
| CD-CYS102SER DTXR | Descriptor: | CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1BI3
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1G3Y
| ARG80ALA DTXR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, ZINC ION | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2000-10-25 | Release date: | 2001-10-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity. Acta Crystallogr.,Sect.D, 57, 2001
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1F5T
| DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE | Descriptor: | 43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION | Authors: | Chen, S, White, A, Love, J, Murphy, J.R, Ringe, D. | Deposit date: | 2000-06-15 | Release date: | 2000-09-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Methyl groups of thymine bases are important for nucleic acid recognition by DtxR. Biochemistry, 39, 2000
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1DPR
| STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE | Descriptor: | DIPHTHERIA TOX REPRESSOR | Authors: | Schiering, N, Tao, X, Murphy, J, Petsko, G.A, Ringe, D. | Deposit date: | 1995-02-06 | Release date: | 1995-09-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. Proc.Natl.Acad.Sci.USA, 92, 1995
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1DDN
| DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX | Descriptor: | 33 BASE DNA CONTAINING TOXIN OPERATOR, DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | Authors: | White, A, Ding, X, Vanderspek, J.C, Murphy, J.R, Ringe, D. | Deposit date: | 1998-06-23 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature, 394, 1998
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1C0W
| CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ... | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | Deposit date: | 1999-07-22 | Release date: | 2000-07-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. J.Mol.Biol., 292, 1999
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1BYM
| SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OF DIPHTHERIA TOXIN REPRESSOR | Descriptor: | PROTEIN (DIPHTHERIA TOXIN REPRESSOR) | Authors: | Wang, G, Wylie, G.P, Twigg, P.D, Caspar, D.L.D, Murphy, J.R, Logan, T.M. | Deposit date: | 1998-10-17 | Release date: | 1998-10-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein. Proc.Natl.Acad.Sci.USA, 96, 1999
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1QVP
| C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226. | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Marin, V, Bhattacharya, N, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-28 | Release date: | 2004-11-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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1QW1
| Solution Structure of the C-Terminal Domain of DtxR residues 110-226 | Descriptor: | Diphtheria toxin repressor | Authors: | Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Love, J.F, Murphy, J.R, Logan, T.M. | Deposit date: | 2003-08-29 | Release date: | 2005-03-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry, 44, 2005
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