PDB Search results for query - Protein Data Bank Japan

PDB: 52 results

Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor:	3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:	Skene, R.J.
Deposit date:	2015-12-01
Release date:	2016-01-13
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.91 Å)
Cite:	Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors. J.Med.Chem., 59, 2016

Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with TYK2 activation loop phosphopeptide
Descriptor:	Non-receptor tyrosine-protein kinase TYK2 activation loop phosphopeptide, Tyrosine-protein phosphatase non-receptor type 1
Authors:	Morris, R, Kershaw, N.J, Babon, J.J.
Deposit date:	2022-10-26
Release date:	2023-08-16
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.99 Å)
Cite:	Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023