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PDB: 11 results
4IUJ
Structure of Polymerase acid protein (PA) from Influenzavirus A Influenza A virus A, WILSON-SMITH/1933 (H1N1)
Descriptor:
Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2013-01-21
Release date:
2013-02-06
Last modified:
2023-09-20
Method:
X-RAY DIFFRACTION (1.9 Å)
Cite:
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Sci Rep, 4, 2014
5IEQ
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-747 1-(4-chlorophenyl)-1H-imidazole
Descriptor:
1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, DIMETHYL SULFOXIDE, Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.2 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5IF5
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to EBSI-39 (2,3-dichlorophenyl)methanol
Descriptor:
(2,3-dichlorophenyl)methanol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ...
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-03-08
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.25 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5IF8
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine
Descriptor:
1,2-ETHANEDIOL, 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine, CHLORIDE ION, ...
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.3 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5IF2
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-576 (5,6-dichloro-1H-1,3-benzodiazol-2-yl)methanol
Descriptor:
(5,6-dichloro-1H-benzimidazol-2-yl)methanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.35 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5V0U
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4723 4-(5-chlorothiophen-2-yl)-1H-pyrazole
Descriptor:
4-(5-chlorothiophen-2-yl)-1H-pyrazole, Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2017-02-28
Release date:
2017-03-08
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.45 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase
To Be Published
5IFB
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4719 5-chloro-2-(1H-imidazol-1-yl)aniline
Descriptor:
5-chloro-2-(1H-imidazol-1-yl)aniline, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (2.45 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
6CFP
CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE
Descriptor:
1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2018-02-15
Release date:
2018-04-11
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (2.45 Å)
Cite:
CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE
To Be Published
5IFD
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole
Descriptor:
1-(4-fluorophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.65 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5IFC
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole
Descriptor:
1-(4-bromophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2024-03-06
Method:
X-RAY DIFFRACTION (2.65 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
5IF7
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Descriptor:
DIMETHYL SULFOXIDE, N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Polymerase acidic protein
Authors:
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:
2016-02-25
Release date:
2017-02-22
Last modified:
2023-09-27
Method:
X-RAY DIFFRACTION (2.65 Å)
Cite:
Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
To Be Published
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PDB entries from 2024-07-31