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PDB: 8 results

3TM0
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Butirosin A Complex
Descriptor: (2S)-4-amino-N-[(1R,2S,3R,4R,5S)-5-amino-4-[(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxy-3-(beta-D-xylofuranosyloxy)cyclohexyl]-2-hydroxybutanamide, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ...
Authors:Berghuis, A.M, Fong, D.H.
Deposit date:2011-08-30
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics.
Antimicrob.Agents Chemother., 53, 2009
2BKK
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Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ...
Authors:Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G.
Deposit date:2005-02-16
Release date:2005-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein
Structure, 13, 2005
3Q2J
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex
Descriptor: Aminoglycoside 3'-phosphotransferase, CALCIUM ION, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE
Authors:Fong, D.H, Xiong, B, Hwang, J, Berghuis, A.M.
Deposit date:2010-12-20
Release date:2011-05-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1501 Å)
Cite:Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Plos One, 6, 2011
1J7L
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, MAGNESIUM ION
Authors:Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M.
Deposit date:2001-05-17
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
1J7U
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Complex
Descriptor: AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M.
Deposit date:2001-05-18
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
1L8T
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Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Kanamycin A Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 3'-Phosphotransferase, KANAMYCIN A, ...
Authors:Fong, D.H, Berghuis, A.M.
Deposit date:2002-03-21
Release date:2002-06-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.
EMBO J., 21, 2002
2B0Q
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Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Neomycin B Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ...
Authors:Fong, D.H, Berghuis, A.M.
Deposit date:2005-09-14
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.
Embo J., 21, 2002
1J7I
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Apoenzyme
Descriptor: AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE
Authors:Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001

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