1JID
 
 | | Human SRP19 in complex with helix 6 of Human SRP RNA | | Descriptor: | HELIX 6 OF HUMAN SRP RNA, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN | | Authors: | Wild, K, Sinning, I, Cusack, S. | | Deposit date: | 2001-07-02 | | Release date: | 2001-10-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of an early protein-RNA assembly complex of the signal recognition particle.
Science, 294, 2001
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7QWQ
 | | Ternary complex of ribosome nascent chain with SRP and NAC | | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | | Deposit date: | 2022-01-25 | | Release date: | 2022-03-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
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1MFQ
 | | Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle | | Descriptor: | 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Kuglstatter, A, Oubridge, C, Nagai, K. | | Deposit date: | 2002-08-13 | | Release date: | 2002-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Induced structural changes of 7SL RNA during the assembly of human
signal recognition particle
Nat.Struct.Biol., 9, 2002
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7NFX
 | | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Jomaa, A, Lee, J.H, Shan, S, Ban, N. | | Deposit date: | 2021-02-08 | | Release date: | 2021-06-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
Sci Adv, 7, 2021
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5M73
 | | Structure of the human SRP S domain with SRP72 RNA-binding domain | | Descriptor: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | | Deposit date: | 2016-10-26 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
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4P3E
 | | Structure of the human SRP S domain | | Descriptor: | MAGNESIUM ION, SRP RNA (124-mer), Signal recognition particle 19 kDa protein, ... | | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | | Deposit date: | 2014-03-07 | | Release date: | 2014-04-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation.
Science, 344, 2014
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3KTV
 | | Crystal structure of the human SRP19/S-domain SRP RNA complex | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... | | Authors: | Wild, K, Bange, G, Bozkurt, G, Sinning, I. | | Deposit date: | 2009-11-26 | | Release date: | 2010-02-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural insights into the assembly of the human and archaeal signal recognition particles.
Acta Crystallogr.,Sect.D, 66, 2010
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2J37
 | | MODEL OF MAMMALIAN SRP BOUND TO 80S RNCS | | Descriptor: | 60S RIBOSOMAL PROTEIN L23, RIBOSOMAL PROTEIN L31, RIBOSOMAL PROTEIN L35, ... | | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | | Deposit date: | 2006-08-18 | | Release date: | 2006-11-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Following the signal sequence from ribosomal tunnel exit to signal recognition particle.
Nature, 444, 2006
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1RY1
 | | Structure of the signal recognition particle interacting with the elongation-arrested ribosome | | Descriptor: | SRP Alu domain, SRP RNA, SRP S domain, ... | | Authors: | Halic, M, Becker, T, Pool, M.R, Spahn, C.M, Grassucci, R.A, Frank, J, Beckmann, R. | | Deposit date: | 2003-12-19 | | Release date: | 2004-04-20 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Nature, 427, 2004
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