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PDB: 2 results

2B7F
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BU of 2b7f by Molmil
Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design
Descriptor: (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION
Authors:Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A.
Deposit date:2005-10-04
Release date:2005-12-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design
Proc.Natl.Acad.Sci.Usa, 102, 2005
4YDG
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BU of 4ydg by Molmil
Crystal structure of compound 10 in complex with HTLV-1 Protease
Descriptor: HTLV-1 protease, N,N'-(3S,4S)-PYRROLIDINE-3,4-DIYLBIS(4-AMINO-N-BENZYLBENZENESULFONAMIDE), SULFATE ION
Authors:Kuhnert, M, Blum, A, Steuber, H, Diederich, W.E.
Deposit date:2015-02-22
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors.
J.Med.Chem., 58, 2015

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