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PDB: 30 results

3V4U
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BU of 3v4u by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-12-15
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UO1
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BU of 3uo1 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-11-16
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3V52
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BU of 3v52 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ...
Authors:Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H.
Deposit date:2011-12-15
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UYR
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Structure of a monoclonal antibody complexed with its MHC-I antigen
Descriptor: 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ...
Authors:Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
Deposit date:2011-12-06
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
8D5N
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BU of 8d5n by Molmil
Crystal structure of Ld-HF10
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Wang, Y, Dai, S.
Deposit date:2022-06-05
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptide Centric V beta Specific Germline Contacts Shape a Specialist T Cell Response.
Front Immunol, 13, 2022
6L9K
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H2-Ld a1a2 complexed with A5 peptide
Descriptor: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
3VJ6
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BU of 3vj6 by Molmil
Structure of the MHC class Ib molecule Qa-1b
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-37 alpha chain, ...
Authors:Zeng, L, Clements, C.S, Rossjohn, J.
Deposit date:2011-10-12
Release date:2012-03-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b
J.Immunol., 188, 2012
4MS8
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BU of 4ms8 by Molmil
42F3 TCR pCPB9/H-2Ld Complex
Descriptor: 42F3 alpha, 42F3 beta, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-09-18
Release date:2014-09-24
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
3ERY
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BU of 3ery by Molmil
Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors
Descriptor: 2-oxoglutarate dehydrogenase E1 peptide, H-2 class I histocompatibility antigen
Authors:Huang, R.H, Jones, L.L.
Deposit date:2008-10-03
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors
Biochemistry, 47, 2008
5VCL
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BU of 5vcl by Molmil
Structure of the Qdm peptide bound to Qa-1a
Descriptor: Beta-2-microglobulin, GLYCEROL, H2-T23 protein, ...
Authors:Ying, G, Zajonc, D.M.
Deposit date:2017-03-31
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of Qa-1a with bound Qa-1 determinant modifier peptide.
PLoS ONE, 12, 2017
3TJH
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BU of 3tjh by Molmil
42F3-p3A1/H2-Ld complex
Descriptor: 42F3 alpha, 42F3 beta, H2-Ld SBM2, ...
Authors:Adams, J.J, Kruse, A, Kranz, D.M, Garcia, K.C.
Deposit date:2011-08-24
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
2OI9
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BU of 2oi9 by Molmil
Structure of the 2C/Ld/QL9 allogeneic complex
Descriptor: Major Histocompatibility Complex protein, T cell receptor alpha chain, T cell receptor beta chain, ...
Authors:Garcia, K.C, Colf, L.A.
Deposit date:2007-01-10
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
6L9L
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1D4 TCR recognition of H2-Ld a1a2 A5 Peptide Complexes
Descriptor: H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, T Cell Receptor
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
1LD9
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BU of 1ld9 by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF AN H-2LD PEPTIDE COMPLEX EXPLAINS THE UNIQUE INTERACTION OF LD WITH BETA2M AND PEPTIDE
Descriptor: BETA-2 MICROGLOBULIN, MHC CLASS I H-2LD HEAVY CHAIN, NANO-PEPTIDE
Authors:Balendiran, G.K, Solheim, J.C, Young, A.C.M, Hansen, T.H, Nathenson, S.G, Sacchettini, J.C.
Deposit date:1997-04-24
Release date:1998-05-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide.
Proc.Natl.Acad.Sci.USA, 94, 1997
2E7L
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BU of 2e7l by Molmil
Structure of a high-affinity mutant of the 2C TCR in complex with Ld/QL9
Descriptor: Beta-chain, Cytotoxic Tcell receptor, H-2 class I histocompatibility antigen, ...
Authors:Garcia, K.C, Colf, L.A.
Deposit date:2007-01-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:How a single T cell receptor recognizes both self and foreign MHC.
Cell(Cambridge,Mass.), 129, 2007
8D5Q
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BU of 8d5q by Molmil
TCR TG6 in complex with Ld-HF10
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dense granule protein 6, HF10 peptide, ...
Authors:Wang, Y, Dai, S.
Deposit date:2022-06-05
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Peptide Centric V beta Specific Germline Contacts Shape a Specialist T Cell Response.
Front Immunol, 13, 2022
4MXQ
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BU of 4mxq by Molmil
42F3 TCR pCPC5/H-2Ld Complex
Descriptor: 42F3 alpha VmVh chimera, 42F3 beta VmVh chimera, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-09-26
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
6L9N
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BU of 6l9n by Molmil
H2-Ld complexed with A5 peptide
Descriptor: MHC, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, b2m
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
6L9M
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BU of 6l9m by Molmil
H2-Ld complexed with AH1 peptide
Descriptor: H2-Ld, SER-PRO-SER-TYR-VAL-TYR-HIS-GLN-PHE, b2m
Authors:Wei, P.C, Yin, L.
Deposit date:2019-11-10
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021
8UMO
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BU of 8umo by Molmil
Murine CD94-NKG2A receptor in complex with Qa-1b presenting AMAPRTLLL
Descriptor: BROMIDE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:MacLachlan, B.J, Rossjohn, J, Vivian, J.P.
Deposit date:2023-10-18
Release date:2024-01-17
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the murine CD94-NKG2A receptor in complex with Qa-1 b presenting an MHC-I leader peptide.
Febs J., 291, 2024
3TF7
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BU of 3tf7 by Molmil
42F3 QL9/H2-Ld complex
Descriptor: 42F3 Mut7 scFv (42F3 alpha chain, linker, 42F3 beta chain), ...
Authors:Adams, J.J, Kranz, D.M, Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TFK
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BU of 3tfk by Molmil
42F3-p4B10/H2-Ld
Descriptor: 42F3 alpha, 42F3 beta, H2-Ld SBM2, ...
Authors:Adams, J.J, Kranz, D.M, Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
4NHU
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BU of 4nhu by Molmil
The M33 TCR p3M33l/H-2 Ld Complex
Descriptor: 2C m33 alpha VmCh chimera, 2C m33 beta VmCh chimera, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-11-05
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Interrogating TCR Signal Strength and Cross-Reactivity by Yeast Display of pMHC
To be Published
4N0C
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BU of 4n0c by Molmil
42F3 TCR pCPE3/H-2Ld complex
Descriptor: 42F3 VmCh alpha, 42F3 VmCh beta, H-2 class I histocompatibility antigen, ...
Authors:Birnbaum, M.E, Adams, J.J, Garcia, K.C.
Deposit date:2013-10-01
Release date:2015-08-19
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
3E3Q
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BU of 3e3q by Molmil
Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
Descriptor: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, ...
Authors:Colf, L.A, Garcia, K.C.
Deposit date:2008-08-07
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.
J.Immunol., 181, 2008

 

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