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PDB: 47 results
7R57
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BU of 7r57 by Molmil
Escherichia coli type II Asparaginase N24S mutant in its apo form
Descriptor: L-asparaginase 2
Authors:Maggi, M, Scotti, C.
Deposit date:2022-02-10
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Aspects of E. coli Type II Asparaginase in Complex with Its Secondary Product L-Glutamate.
Int J Mol Sci, 23, 2022
6PAC
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BU of 6pac by Molmil
E. coli L-asparaginase II in complex with L-Asp at pH 5.6
Descriptor: ASPARTIC ACID, IMIDAZOLE, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
5MQ5
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BU of 5mq5 by Molmil
A protease-resistant N24S Escherichia coli Asparaginase mutant with outstanding stability and enhanced anti-leukaemic activity
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Maggi, M, Mittelman, S.D, Parmentier, J.H, Whitmire, J.M, Merrell, D.S, Scotti, C.
Deposit date:2016-12-20
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro.
Sci Rep, 7, 2017
7P9C
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BU of 7p9c by Molmil
Escherichia coli type II L-asparaginase
Descriptor: L-asparaginase 2
Authors:Maggi, M, Scotti, C.
Deposit date:2021-07-27
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Revealing Escherichia coli type II L-asparaginase active site flexible loop in its open, ligand-free conformation.
Sci Rep, 11, 2021
8ECD
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BU of 8ecd by Molmil
E. coli L-asparaginase II mutant (V27T) in complex with L-Asp
Descriptor: 1,2-ETHANEDIOL, ASPARTIC ACID, CITRIC ACID, ...
Authors:Strzelczyk, P, Wlodawer, A, Lubkowski, J.
Deposit date:2022-09-01
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The E. coli L-asparaginase V27T mutant: structural and functional characterization and comparison with theoretical predictions.
Febs Lett., 596, 2022
6PA3
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BU of 6pa3 by Molmil
E. coli L-asparaginase II double mutant (T89V,K162T) in complex with L-Asn at pH 7.0
Descriptor: ASPARAGINE, IMIDAZOLE, L-asparaginase 2, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6PAB
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BU of 6pab by Molmil
E. coli L-asparaginase II in complex with L-Asp at pH 7.0
Descriptor: ASPARTIC ACID, CITRIC ACID, IMIDAZOLE, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6V23
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BU of 6v23 by Molmil
Ligand-free L-aspraginase II from E. coli (EcAII)
Descriptor: L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6NXB
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BU of 6nxb by Molmil
ECAII IN COMPLEX WITH CITRATE AT PH 7
Descriptor: CITRIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6V25
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BU of 6v25 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V26
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BU of 6v26 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
7M11
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BU of 7m11 by Molmil
L-asparaginase from Escherichia coli with bound Aspartic acid
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Souza, T.A.C.B, Morais, S.B, Morini, F.S, Meissner, G.O.
Deposit date:2021-03-11
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:L-asparaginase from Escherichia coli: Novel insights about the behavior of flexible part of the active site
To Be Published
6PAA
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BU of 6paa by Molmil
E. coli L-asparaginase II mutant (T12V) in complex with L-Asp at pH 5.5
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6PA4
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BU of 6pa4 by Molmil
E. coli L-asparaginase II double mutant (T89V,K162T) in complex with L-Asp at pH 7.0
Descriptor: ASPARTIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6NX8
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BU of 6nx8 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 6.2
Descriptor: ACETIC ACID, CITRIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
8ECE
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BU of 8ece by Molmil
E. coli L-asparaginase II mutant (V27T) in complex with L-Glu
Descriptor: 1,2-ETHANEDIOL, GLUTAMIC ACID, L-asparaginase 2
Authors:Strzelczyk, P, Wlodawer, A, Lubkowski, J.
Deposit date:2022-09-01
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The E. coli L-asparaginase V27T mutant: structural and functional characterization and comparison with theoretical predictions.
Febs Lett., 596, 2022
6PA9
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BU of 6pa9 by Molmil
E. coli L-asparaginase II mutant (T12V) in complex with L-Asn at pH 7.0
Descriptor: ASPARAGINE, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6V24
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BU of 6v24 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp. Covalent acyl-enzyme intermediate.
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V2G
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BU of 6v2g by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp. Covalent acyl-enzyme intermediate and tetrahedral intermediate.
Descriptor: L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6PA8
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BU of 6pa8 by Molmil
ECAII(T89V,K162T) MUTANT IN COMPLEX WITH L-ASN AT PH 7.0
Descriptor: ASPARAGINE, CITRATE ANION, GLYCEROL, ...
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
6PA2
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BU of 6pa2 by Molmil
E. coli L-asparaginase II mutant (K162M) in complex with L-Asp at pH 5.6
Descriptor: ASPARTIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-06-11
Release date:2019-09-04
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Geometric considerations support the double-displacement catalytic mechanism of l-asparaginase.
Protein Sci., 28, 2019
7R5Q
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BU of 7r5q by Molmil
Escherichia coli type II Asparaginase N24S mutant in complex with GLU
Descriptor: GLUTAMIC ACID, L-asparaginase 2
Authors:Maggi, M, Scotti, C.
Deposit date:2022-02-11
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Aspects of E. coli Type II Asparaginase in Complex with Its Secondary Product L-Glutamate.
Int J Mol Sci, 23, 2022
6NXA
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BU of 6nxa by Molmil
ECAII(D90T,K162T) MUTANT AT PH 7
Descriptor: ACETIC ACID, GLYCEROL, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6V28
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BU of 6v28 by Molmil
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asp
Descriptor: GLYCEROL, IMIDAZOLE, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
1NNS
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BU of 1nns by Molmil
L-asparaginase of E. coli in C2 space group and 1.95 A resolution
Descriptor: ASPARTIC ACID, L-asparaginase II
Authors:Sanches, M, Barbosa, J.A.R.G, de Oliveira, R.T, Neto, J.A.A, Polikarpov, I.
Deposit date:2003-01-14
Release date:2003-03-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural comparison of Escherichia coli L-asparaginase in two monoclinic space groups.
Acta Crystallogr.,Sect.D, 59, 2003

 

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