Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 575 results
1AZ8
DownloadVisualize
BU of 1az8 by Molmil
BOVINE TRYPSIN COMPLEXED TO BIS-PHENYLAMIDINE INHIBITOR
Descriptor: +/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE, TRYPSIN
Authors:Alexander, R, Smallwood, A.
Deposit date:1997-11-26
Release date:1999-01-13
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Unexpected Binding Mode of a Bis-Phenylamidine Factor Xa Inhibitor Complexed to Bovine Trypsin
To be Published
3UQO
DownloadVisualize
BU of 3uqo by Molmil
Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor
Descriptor: 3-(3-carbamimidoylphenyl)-N-(2'-sulfamoylbiphenyl-4-yl)-1,2-oxazole-4-carboxamide, CALCIUM ION, Cationic trypsin
Authors:Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T.
Deposit date:2011-11-21
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
7BS2
DownloadVisualize
BU of 7bs2 by Molmil
Bovine Pancreatic Trypsin with serotonin (Room Temperature)
Descriptor: CALCIUM ION, Cationic trypsin, SEROTONIN, ...
Authors:Maeki, M, Ito, S, Takeda, R, Funakubo, T, Ueno, G, Ishida, A, Tani, H, Yamamoto, M, Tokeshi, M.
Deposit date:2020-03-30
Release date:2020-08-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis.
Chem Sci, 11, 2020
1PPC
DownloadVisualize
BU of 1ppc by Molmil
GEOMETRY OF BINDING OF THE BENZAMIDINE-AND ARGININE-BASED INHIBITORS N-ALPHA-(2-NAPHTHYL-SULPHONYL-GLYCYL)-DL-P-AMIDINOPHENYLALANYL-PIPERIDINE (NAPAP) AND (2R,4R)-4-METHYL-1-[N-ALPHA-(3-METHYL-1,2,3,4-TETRAHYDRO-8-QUINOLINESULPHONYL)-L-ARGINYL]-2-PIPERIDINE CARBOXYLIC ACID (MQPA) TO HUMAN ALPHA-THROMBIN: X-RAY CRYSTALLOGRAPHIC DETERMINATION OF THE NAPAP-TRYPSIN COMPLEX AND MODELING OF NAPAP-THROMBIN AND MQPA-THROMBIN
Descriptor: 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, CALCIUM ION, TRYPSIN
Authors:Bode, W, Turk, D.
Deposit date:1991-10-24
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydr quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-thrombin.X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin.
Eur.J.Biochem., 193, 1990
1G3B
DownloadVisualize
BU of 1g3b by Molmil
BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASE MAGNESIUM(II) CHELATE
Descriptor: 2-(5-CARBAMIMIDOYL-2-HYDROXY-BENZYLAMINO)-PROPIONIC ACID, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Toyota, E, Ng, K.K.S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G.
Deposit date:2000-10-23
Release date:2001-01-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates.
J.Mol.Biol., 305, 2001
1Y3U
DownloadVisualize
BU of 1y3u by Molmil
TRYPSIN INHIBITOR COMPLEX
Descriptor: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL-1-ISOPROPYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE, CALCIUM ION, Trypsin, ...
Authors:Fokkens, J, Obst, U, Heine, A, Diederich, F, Klebe, G.
Deposit date:2004-11-26
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Thermodynamic Characterisation of Protein-Inhibitor-Complexes of Thrombin and Trypsin Inhibitors
To be Published
3V12
DownloadVisualize
BU of 3v12 by Molmil
Bovine trypsin variant X(tripleGlu217Phe227) in complex with small molecule inhibitor
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
Authors:Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
1TGC
DownloadVisualize
BU of 1tgc by Molmil
ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY
Descriptor: CALCIUM ION, TRYPSINOGEN
Authors:Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R.
Deposit date:1981-10-26
Release date:1982-03-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography
Acta Crystallogr.,Sect.B, 38, 1982
2ZDL
DownloadVisualize
BU of 2zdl by Molmil
Exploring trypsin S3 pocket
Descriptor: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
Authors:Baum, B, Brandt, T, Heine, A, Klebe, G.
Deposit date:2007-11-26
Release date:2008-10-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
1TNJ
DownloadVisualize
BU of 1tnj by Molmil
PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS
Descriptor: 2-PHENYLETHYLAMINE, CALCIUM ION, TRYPSIN
Authors:Kurinov, I, Harrison, R.W.
Deposit date:1994-07-21
Release date:1994-11-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Prediction of new serine proteinase inhibitors.
Nat.Struct.Biol., 1, 1994
1TNH
DownloadVisualize
BU of 1tnh by Molmil
PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS
Descriptor: 4-FLUOROBENZYLAMINE, CALCIUM ION, TRYPSIN
Authors:Kurinov, I, Harrison, R.W.
Deposit date:1994-07-21
Release date:1994-11-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Prediction of new serine proteinase inhibitors.
Nat.Struct.Biol., 1, 1994
1G3D
DownloadVisualize
BU of 1g3d by Molmil
BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASE COPPER (II) CHELATE
Descriptor: 2-(5-CARBAMIMIDOYL-2-HYDROXY-BENZYLAMINO)-PROPIONIC ACID, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Toyota, E, Ng, K.K.S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G.
Deposit date:2000-10-23
Release date:2001-01-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates.
J.Mol.Biol., 305, 2001
3UNS
DownloadVisualize
BU of 3uns by Molmil
Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
Authors:Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T.
Deposit date:2011-11-16
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
1NTP
DownloadVisualize
BU of 1ntp by Molmil
USE OF THE NEUTRON DIFFRACTION H/D EXCHANGE TECHNIQUE TO DETERMINE THE CONFORMATIONAL DYNAMICS OF TRYPSIN
Descriptor: BETA-TRYPSIN, PHOSPHORYLISOPROPANE
Authors:Kossiakoff, A.A.
Deposit date:1987-09-16
Release date:1988-01-16
Last modified:2017-11-29
Method:NEUTRON DIFFRACTION (1.8 Å)
Cite:Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin
Basic Life Sci., 27, 1984
1TNG
DownloadVisualize
BU of 1tng by Molmil
PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS
Descriptor: AMINOMETHYLCYCLOHEXANE, CALCIUM ION, TRYPSIN
Authors:Kurinov, I, Harrison, R.W.
Deposit date:1994-07-21
Release date:1994-11-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Prediction of new serine proteinase inhibitors.
Nat.Struct.Biol., 1, 1994
1G3C
DownloadVisualize
BU of 1g3c by Molmil
BOVINE BETA-TRYPSIN BOUND TO PARA-AMIDINO SCHIFF BASE IRON(III) CHELATE
Descriptor: 2-(4-CARBAMIMIDOYL-2-HYDROXY-BENZYLAMINO)-PROPIONIC ACID, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Toyota, E, Ng, K.K.S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G.
Deposit date:2000-10-23
Release date:2001-01-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates.
J.Mol.Biol., 305, 2001
1G3E
DownloadVisualize
BU of 1g3e by Molmil
BOVINE BETA-TRYPSIN BOUND TO PARA-AMIDINO SCHIFF-BASE COPPER (II) CHELATE
Descriptor: 2-(4-CARBAMIMIDOYL-2-HYDROXY-BENZYLAMINO)-PROPIONIC ACID, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Toyota, E, Ng, K.K.S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G.
Deposit date:2000-10-23
Release date:2001-01-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates.
J.Mol.Biol., 305, 2001
3A89
DownloadVisualize
BU of 3a89 by Molmil
Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 4 hours)
Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ...
Authors:Yamane, J, Yao, M, Tanaka, I.
Deposit date:2009-10-05
Release date:2010-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:In-Crystal Chemical Ligation for Drug Discovery
To be Published
3A7Z
DownloadVisualize
BU of 3a7z by Molmil
Crystal Structure of Trypsin complexed with (E)-4-((1-methylpiperidin-4-yloxyimino)methyl)benzimidamide (soaking 3hours)
Descriptor: (E)-4-((1-methylpiperidin-4-yloxyimino)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ...
Authors:Yamane, J, Yao, M, Tanaka, I.
Deposit date:2009-10-05
Release date:2010-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:In-Crystal Chemical Ligation for Drug Discovery
To be Published
1TGB
DownloadVisualize
BU of 1tgb by Molmil
CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. II. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN
Descriptor: CALCIUM ION, TRYPSINOGEN
Authors:Bode, W, Fehlhammer, H, Huber, R.
Deposit date:1979-03-07
Release date:1979-06-13
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin.
J.Mol.Biol., 111, 1977
1BJV
DownloadVisualize
BU of 1bjv by Molmil
BETA-TRYPSIN COMPLEXED WITH APPU
Descriptor: 1-(2-AMIDINOPHENYL)-3-(PHENOXYPHENYL)UREA, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Presnell, S, Patil, G, Mura, C, Jude, K, Conley, J, Kam, C, Bertrand, J, Powers, J, Williams, L.
Deposit date:1998-06-29
Release date:1998-12-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Oxyanion-mediated inhibition of serine proteases.
Biochemistry, 37, 1998
1BJU
DownloadVisualize
BU of 1bju by Molmil
BETA-TRYPSIN COMPLEXED WITH ACPU
Descriptor: 1-(4-AMIDINOPHENYL)-3-(4-CHLOROPHENYL)UREA, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Presnell, S, Patil, G, Mura, C, Jude, K, Conley, J, Kam, C, Bertrand, J, Powers, J, Williams, L.
Deposit date:1998-06-29
Release date:1998-12-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Oxyanion-mediated inhibition of serine proteases.
Biochemistry, 37, 1998
1V2V
DownloadVisualize
BU of 1v2v by Molmil
Benzamidine in complex with bovine trypsin variant X(SSAI)bT.C1
Descriptor: BENZAMIDINE, CALCIUM ION, SULFATE ION, ...
Authors:Rauh, D, Klebe, G, Stubbs, M.T.
Deposit date:2003-10-17
Release date:2004-06-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding protein-ligand interactions: the price of protein flexibility
J.Mol.Biol., 335, 2004
1V2N
DownloadVisualize
BU of 1v2n by Molmil
Potent factor XA inhibitor in complex with bovine trypsin variant X(99/175/190)bT
Descriptor: 2,7-BIS-(4-AMIDINOBENZYLIDENE)-CYCLOHEPTAN-1-ONE, CALCIUM ION, Trypsin
Authors:Rauh, D, Klebe, G, Stubbs, M.T.
Deposit date:2003-10-17
Release date:2004-06-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding protein-ligand interactions: the price of protein flexibility
J.Mol.Biol., 335, 2004
1QBN
DownloadVisualize
BU of 1qbn by Molmil
Bovine Trypsin 2-[amino(imino)methyl]-2-hydroxyphenoxy]-6-[3-(4,5-dihydro-1H-imidazol-2-yl)phenoxy]pyridine-4-carboxylic Acid (ZK-806688) Complex
Descriptor: 2-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-6-[3-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDINE-4-CARBOXYLIC ACID, CALCIUM ION, PROTEIN (TRYPSIN)
Authors:Whitlow, M.
Deposit date:1999-04-25
Release date:2000-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.
Acta Crystallogr.,Sect.D, 55, 1999

225946

PDB entries from 2024-10-09

PDB statisticsPDBj update infoContact PDBjnumon