7LWH
| Human neurofibromin 2/merlin residues 1-339 in complex with LATS1 | Descriptor: | GLYCEROL, IMIDAZOLE, Merlin, ... | Authors: | Primi, M.C, Rangarajan, E.S, Izard, T. | Deposit date: | 2021-03-01 | Release date: | 2021-08-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.606 Å) | Cite: | Conformational flexibility determines the Nf2/merlin tumor suppressor functions. Matrix Biol Plus, 12, 2021
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5BRK
| pMob1-Lats1 complex | Descriptor: | MOB kinase activator 1A, Serine/threonine-protein kinase LATS1, ZINC ION | Authors: | Ni, L, Luo, X. | Deposit date: | 2015-05-31 | Release date: | 2015-07-08 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling. Genes Dev., 29, 2015
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4ZRK
| Merlin-FERM and Lats1 complex | Descriptor: | Merlin, Serine/threonine-protein kinase LATS1 | Authors: | Lin, Z, Li, Y, Wei, Z, Zhang, M. | Deposit date: | 2015-05-12 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.316 Å) | Cite: | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
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5B5W
| Crystal structure of MOB1-LATS1 NTR domain complex | Descriptor: | MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ZINC ION | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | Deposit date: | 2016-05-24 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.957 Å) | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway Sci Rep, 6, 2016
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