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PDB: 2 results

7LAF
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BU of 7laf by Molmil
15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
Descriptor: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B
Authors:Newcomer, M.E, Gilbert, N.C, Neau, D.B.
Deposit date:2021-01-06
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg.Med.Chem., 46, 2021
4NRE
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BU of 4nre by Molmil
The structure of human 15-lipoxygenase-2 with a substrate mimic
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Arachidonate 15-lipoxygenase B, CALCIUM ION, ...
Authors:Kobe, M.J, Neau, D.B, Mitchell, C.E, Bartlett, S.G, Newcomer, M.E.
Deposit date:2013-11-26
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:The structure of human 15-lipoxygenase-2 with a substrate mimic.
J.Biol.Chem., 289, 2014

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