3SPA
 
 | | Crystal Structure of Human Mitochondrial RNA Polymerase | | Descriptor: | CHLORIDE ION, DNA-directed RNA polymerase, mitochondrial, ... | | Authors: | Ringel, R, Sologub, M, Morozov, Y.I, Litonin, D, Cramer, P, Temiakov, D. | | Deposit date: | 2011-07-01 | | Release date: | 2011-09-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of human mitochondrial RNA polymerase
Nature, 478, 2011
|
|
4BOC
 | | Structure of mitochondrial RNA polymerase elongation complex | | Descriptor: | 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ... | | Authors: | Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P. | | Deposit date: | 2013-05-18 | | Release date: | 2013-09-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
|
|
7PZR
 | | Cryo-EM structure of POLRMT in free form. | | Descriptor: | DNA-directed RNA polymerase, mitochondrial | | Authors: | Das, H, Hallberg, B.M. | | Deposit date: | 2021-10-13 | | Release date: | 2022-11-16 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
|
|
7ZC4
 | | Cryo-EM structure of POLRMT mutant. | | Descriptor: | DNA-directed RNA polymerase, mitochondrial | | Authors: | Das, H, Hallberg, B.M. | | Deposit date: | 2022-03-25 | | Release date: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.
Cell, 185, 2022
|
|
7PZP
 | |
7A8P
 | | Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor. | | Descriptor: | (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid, DNA-directed RNA polymerase, mitochondrial | | Authors: | Hillen, H.S, Bonekamp, N, Peter, B, Felser, A, Bergbrede, T, Choidas, A, Horn, M, Unger, A, di Lucrezia, R, Atanassov, I, Li, X, Koch, U, Menninger, S, Boros, J, Habenberger, P, Giavalisco, P, Cramer, P, Denzel, M, Nussbaumer, P, Klebl, B, Falkenberg, M, Gustafsson, C.M, Larsson, N.G. | | Deposit date: | 2020-08-30 | | Release date: | 2020-12-30 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature, 588, 2020
|
|
5OLA
 | | Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM | | Descriptor: | DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ... | | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | Deposit date: | 2017-07-27 | | Release date: | 2017-10-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.904 Å) | | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
|
|
6ERQ
 | | Structure of the human mitochondrial transcription initiation complex at the HSP promoter | | Descriptor: | DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... | | Authors: | Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. | | Deposit date: | 2017-10-18 | | Release date: | 2017-11-15 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
|
|
6ERP
 | | Structure of the human mitochondrial transcription initiation complex at the LSP promoter | | Descriptor: | DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... | | Authors: | Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. | | Deposit date: | 2017-10-18 | | Release date: | 2017-11-15 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (4.502 Å) | | Cite: | Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
|
|
