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PDB: 4 results

8BPT
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BU of 8bpt by Molmil
Crystal structure of the second bromodomain of BRD5 from Leishmania donovani
Descriptor: Bromo domain-containing protein
Authors:Wilkinson, A.J, Dodson, E.J, Jones, N.G, Borgia, J.
Deposit date:2022-11-17
Release date:2023-09-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery.
Acs Infect Dis., 9, 2023
5TCK
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BU of 5tck by Molmil
Second Bromodomain from Leishmania donovani LdBPK.091320 complexed with Bromosporine
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromosporine, ...
Authors:Lin, L.-H, Hou, C.F.D, Loppnau, P, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC)
Deposit date:2016-09-15
Release date:2016-11-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Second Bromodomain from Leishmania donovani LdBPK.091320 complexed with Bromosporine
To Be Published
5TCM
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BU of 5tcm by Molmil
First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
Descriptor: 1,2-ETHANEDIOL, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Uncharacterized protein
Authors:Lin, Y.H, Hou, C.F.D, Loppnau, P, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC)
Deposit date:2016-09-15
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536
To be published
6BYA
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BU of 6bya by Molmil
Crystal structure of LdBPK_091320 with inhibitor bound
Descriptor: 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole, UNKNOWN ATOM OR ION, Uncharacterized protein
Authors:Dong, A, Lin, Y.H, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Structural Genomics Consortium (SGC)
Deposit date:2017-12-20
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of LdBPK_091320.1 with with inhibitor bound
to be published

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