3W95
 
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8C6D
 | | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate. | | Descriptor: | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, Genome polyprotein, Genome polyprotein (Fragment) | | Authors: | Kingston, N.J, Snowden, J.S, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M. | | Deposit date: | 2023-01-11 | | Release date: | 2023-02-22 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Biorxiv, 2023
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9F5S
 | | EVA71 E096A native particle | | Descriptor: | SPHINGOSINE, VP0, VP1, ... | | Authors: | Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S. | | Deposit date: | 2024-04-30 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.
Plos Pathog., 20, 2024
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9F6A
 | | EVA71 E096A native particle | | Descriptor: | SPHINGOSINE, VP0, VP1, ... | | Authors: | Kingston, N.J, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M, Filman, D.J, Snowden, J.S.S. | | Deposit date: | 2024-04-30 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.
Plos Pathog., 20, 2024
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6Z3Q
 | | Structure of EV71 in complex with a protective antibody 38-1-10A Fab | | Descriptor: | Heavy chain, Light chain, SPHINGOSINE, ... | | Authors: | Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. | | Deposit date: | 2020-05-21 | | Release date: | 2020-09-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71.
Nat Commun, 11, 2020
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6HLW
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6Z3P
 | | Structure of EV71 in complex with a protective antibody 38-3-11A Fab | | Descriptor: | SPHINGOSINE, VP1, VP2, ... | | Authors: | Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. | | Deposit date: | 2020-05-21 | | Release date: | 2020-09-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71.
Nat Commun, 11, 2020
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6I2K
 | | Structure of EV71 complexed with its receptor SCARB2 | | Descriptor: | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhou, D, Zhao, Y, Kotecha, A, Fry, E.E, Kelly, J, Wang, X, Rao, Z, Rowlands, D.J, Ren, J, Stuart, D.I. | | Deposit date: | 2018-11-01 | | Release date: | 2018-11-28 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.
Nat Microbiol, 4, 2019
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