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PDB: 2 results

4XSX
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BU of 4xsx by Molmil
Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-22
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.708 Å)
Cite:CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XSY
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BU of 4xsy by Molmil
Crystal structure of CBR 9379 bound to Escherichia coli RNA polymerase holoenzyme
Descriptor: 3-{[(2,6-dichlorophenyl)carbamoyl]amino}-N-hydroxy-N'-phenyl-5-(trifluoromethyl)benzenecarboximidamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-22
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.007 Å)
Cite:CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015

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