PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #16
Descriptor:	(4M)-4-{(4R)-3-[(2S)-2-methylbutyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(1-methyl-1H-pyrazol-5-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 1
Authors:	Anderson, J.W, Vigers, G.P.
Deposit date:	2023-09-18
Release date:	2024-03-27
Last modified:	2024-04-10
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife, 12, 2024

Co-crystal structure of phosphorylated ERK2 in complex with ERK1/2 inhibitor #8
Descriptor:	(4M)-4-{(4S)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-N-(oxan-4-yl)pyrimidin-2-amine, Mitogen-activated protein kinase 1
Authors:	Anderson, J.W, Vigers, G.P.
Deposit date:	2023-09-18
Release date:	2024-03-27
Last modified:	2024-04-10
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife, 12, 2024