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PDB: 1 results

6FU5
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BU of 6fu5 by Molmil
Structure of the kinase domain of human RIPK2 in complex with the inhibitor CSLP18
Descriptor: Receptor-interacting serine/threonine-protein kinase 2, ~{N}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide
Authors:Pinkas, D.M, Bufton, J.C, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2018-02-26
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
EMBO J., 37, 2018

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