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PDB: 1 results

4EU2
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Crystal structure of 20s proteasome with novel inhibitor K-7174
Descriptor: 1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl]-1,4-diazepane, Proteasome component C1, Proteasome component C11, ...
Authors:Kikuchi, J, Shibayama, N, Yamada, S, Wada, T, Nobuyoshi, M, Izumi, T, Akutsu, M, Kano, Y, Ohki, M, Sugiyama, K, Park, S.-Y, Furukawa, Y.
Deposit date:2012-04-25
Release date:2013-05-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.
Plos One, 8, 2013

226707

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