6SFR
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![BU of 6sfr by Molmil](/molmil-images/mine/6sfr) | SOS1 in Complex with Inhibitor BI-68BS | Descriptor: | 6,7-dimethoxy-~{N}-[(1~{R})-1-phenylethyl]quinazolin-4-amine, IMIDAZOLE, Son of sevenless homolog 1 | Authors: | Kessler, D, Fischer, G, Ramharter, J. | Deposit date: | 2019-08-02 | Release date: | 2020-08-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.917 Å) | Cite: | BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition. Cancer Discov, 11, 2021
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6SCM
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![BU of 6scm by Molmil](/molmil-images/mine/6scm) | SOS1 in Complex with Inhibitor BI-3406 | Descriptor: | 1,2-ETHANEDIOL, IMIDAZOLE, Son of sevenless homolog 1, ... | Authors: | Kessler, D, Fischer, G, Ramharter, J. | Deposit date: | 2019-07-24 | Release date: | 2020-08-26 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.866 Å) | Cite: | BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition. Cancer Discov, 11, 2021
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