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PDB: 1 results

6B3S
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BU of 6b3s by Molmil
Crystal structure of the Fab fragment of necitumumab (Fab11F8) in complex with domain III from a cetuximab resistant variant of EGFR (sEGFRd3-S468R)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Bagchi, A.
Deposit date:2017-09-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Mol. Cancer Ther., 17, 2018

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