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PDB: 1 results

6NHA
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BU of 6nha by Molmil
Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ...
Authors:Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K.
Deposit date:2018-12-21
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Sci Adv, 5, 2019

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