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PDB: 3 results

2OOH
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BU of 2ooh by Molmil
Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11
Descriptor: 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, Macrophage migration inhibitory factor, ...
Authors:Crichlow, G.V, Al-Abed, Y, Lolis, E.
Deposit date:2007-01-25
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOW
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BU of 2oow by Molmil
MIF Bound to a Fluorinated OXIM Derivative
Descriptor: 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Crichlow, G.V, Al-Abed, Y, Lolis, E.
Deposit date:2007-01-26
Release date:2007-06-05
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOZ
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BU of 2ooz by Molmil
Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group)
Descriptor: 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Crichlow, G.V, Al-Abed, Y, Lolis, E.
Deposit date:2007-01-26
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007

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