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PDB: 2 results

5U6B
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BU of 5u6b by Molmil
Structure of the Axl kinase domain in complex with a macrocyclic inhibitor
Descriptor: (10R)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1H-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one, Tyrosine-protein kinase receptor UFO
Authors:Gajiwala, K.S, Grodsky, N.
Deposit date:2016-12-07
Release date:2017-07-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.
J. Biol. Chem., 292, 2017
5U6C
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BU of 5u6c by Molmil
Crystal structure of the Mer kinase domain in complex with a macrocyclic inhibitor
Descriptor: (10R)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1H-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one, Tyrosine-protein kinase Mer
Authors:Gajiwala, K.S, Ferre, R.A.
Deposit date:2016-12-07
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.
J. Biol. Chem., 292, 2017

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