PDB Search results for query - Protein Data Bank Japan

PDB: 1 results

Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase
Descriptor:	CADMIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
Authors:	Yachnin, B.J, Berghuis, A.M.
Deposit date:	2008-09-15
Release date:	2009-05-26
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J.Biol.Chem., 284, 2009