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PDB: 2 results

4HVS
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BU of 4hvs by Molmil
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647
Descriptor: 5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[4-(trifluoromethyl)benzyl]pyridin-2-amine, Mast/stem cell growth factor receptor Kit
Authors:Zhang, Y, Zhang, C.
Deposit date:2012-11-06
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HW7
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BU of 4hw7 by Molmil
Crystal structure of FMS kinase domain with a small molecular inhibitor, PLX647-OME
Descriptor: 5-[(5-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[4-(trifluoromethyl)benzyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor
Authors:Zhang, Y, Zhang, C.
Deposit date:2012-11-07
Release date:2013-03-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9001 Å)
Cite:Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013

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